Hidaka Nobuhiro, Chiba Yoshihide
Department of Perinatology, National Cardiovascular Center, Osaka, Japan.
Arch Gynecol Obstet. 2007 Mar;275(3):219-22. doi: 10.1007/s00404-006-0214-3. Epub 2006 Aug 10.
In the recent years, the association between congenital intestinal atresia and umbilical cord ulceration has been demonstrated; however, this complication is rarely encountered. To the best of our knowledge, only 14 cases on this association have been published previously. We encountered a case of acute intrauterine hemorrhage from an umbilical cord ulcer in a fetus with duodenal atresia that resulted in early neonatal death. There is little information available on the association between congenital intestinal atresia and umbilical cord ulceration. Greater understanding may alter the obstetric management. Although the prevention of sudden perinatal death is considered to be difficult, frequent fetal monitoring and detailed ultrasonographic examinations may facilitate the early detection of this condition, thereby enabling the rescue of the affected fetuses. Further investigation is required to establish the management protocol.
近年来，先天性肠闭锁与脐带溃疡之间的关联已得到证实；然而，这种并发症很少见。据我们所知，此前仅有14例关于这种关联的病例被报道。我们遇到了一例患有十二指肠闭锁的胎儿因脐带溃疡导致急性宫内出血，最终早期新生儿死亡的病例。关于先天性肠闭锁与脐带溃疡之间的关联，目前可用信息很少。更多的了解可能会改变产科管理。尽管预防围产期猝死被认为很困难，但频繁的胎儿监测和详细的超声检查可能有助于早期发现这种情况，从而拯救受影响的胎儿。需要进一步研究以制定管理方案。
