Sieskiewicz Andrzej, Olszewska Ewa, Rogowski Marek, Grycz Ewa
Department of Otolaryngology, Medical University of Bialystok, Bialystok, Poland.
Ann Otol Rhinol Laryngol. 2006 Jul;115(7):490-4. doi: 10.1177/000348940611500702.
The aim of the study was to investigate whether orally administered steroids might improve surgical field conditions during functional endoscopic sinus surgery.
Total blood loss and visualization of the surgical field during the surgical procedure were compared in 2 groups of 18 patients each with severe nasal polyposis. The groups were similar in respect to age, body mass index, general health status, incidence of allergy, bronchial asthma, aspirin triad, and stage of disease. One group received 30 mg of prednisone daily for 5 consecutive days before the operation. The second group served as a control.
Although the total blood loss was only slightly less in the steroid group, the visual conditions of the surgical field improved significantly.
Better surgical field conditions were the results of the powerful anti-inflammatory and antiedematous activity of the drug, which facilitated blood and secretion evacuation from the operated area and prevented the optic system from staining.
本研究旨在调查口服类固醇是否能改善功能性内镜鼻窦手术期间的手术视野状况。
将两组各18例患有严重鼻息肉的患者在手术过程中的总失血量和手术视野可视化情况进行比较。两组在年龄、体重指数、一般健康状况、过敏发生率、支气管哮喘、阿司匹林三联征和疾病分期方面相似。一组在手术前连续5天每天服用30毫克泼尼松。第二组作为对照组。
虽然类固醇组的总失血量仅略少，但手术视野的视觉状况有显著改善。
更好的手术视野状况是该药物强大的抗炎和消肿活性的结果，这有助于从手术区域排出血液和分泌物，并防止视觉系统染色。
