成人法洛四联症手术治疗的长期结果。

Long-term results of surgical treatment of tetralogy of Fallot in adults.

作者信息

Lu X, Wu S, Gu X, Li L, Zhang G, Sun W, Yu J

机构信息

Department of Cardiovascular Surgery, Qilu Hospital, Shandong University, WenHuaXi Road 10, Jinan 250012, China.

出版信息

Thorac Cardiovasc Surg. 2006 Aug;54(5):295-9. doi: 10.1055/s-2006-923959.

DOI:10.1055/s-2006-923959

PMID:16902875

Abstract

BACKGROUND

The long-term results of patients with tetralogy of Fallot surgically treated in adulthood were evaluated to define the real benefit of surgical correction.

METHODS

Between August 1990 and February 2004, 57 patients older than 18 years of age with tetralogy of Fallot received total correction. Forty-two patients (73.7 %) required transannular patch.

RESULTS

Hospital and late mortality were 7.0 % (n = 4) and 5.7 % (n = 3), respectively. One patient was reoperated on to close residual ventricular septal defect. Four patients were lost. Of the remaining 49 patients, the mean follow-up was 65 +/- 38 months (range 11 - 173 months). Actuarial survival was 97.4 +/- 2.5 %, 91 +/- 7 % and 72.8 +/- 17.1 % at 5, 10 and 14 years, respectively. At the latest follow-up, 35 (76.1 %) of the surviving patients presently have NYHA functional class I ( P < 0.01).

CONCLUSION

The overall survival of surgically treated adult patients with tetralogy of Fallot is acceptable. The greatest benefit of total correction at this age is the functional improvement.

摘要

背景

评估成年期接受手术治疗的法洛四联症患者的长期结果，以确定手术矫正的实际益处。

方法

1990年8月至2004年2月，57例年龄超过18岁的法洛四联症患者接受了根治手术。42例患者（73.7%）需要跨环补片。

结果

住院死亡率和晚期死亡率分别为7.0%（n = 4）和5.7%（n = 3）。1例患者再次手术关闭残余室间隔缺损。4例患者失访。其余49例患者的平均随访时间为65±38个月（范围11 - 173个月）。5年、10年和14年的精算生存率分别为97.4±2.5%、91±7%和72.8±17.1%。在最近一次随访时，35例（76.1%）存活患者目前的心功能分级为纽约心脏协会（NYHA）I级（P < 0.01）。