Lu X, Wu S, Gu X, Li L, Zhang G, Sun W, Yu J
Department of Cardiovascular Surgery, Qilu Hospital, Shandong University, WenHuaXi Road 10, Jinan 250012, China.
Thorac Cardiovasc Surg. 2006 Aug;54(5):295-9. doi: 10.1055/s-2006-923959.
The long-term results of patients with tetralogy of Fallot surgically treated in adulthood were evaluated to define the real benefit of surgical correction.
Between August 1990 and February 2004, 57 patients older than 18 years of age with tetralogy of Fallot received total correction. Forty-two patients (73.7 %) required transannular patch.
Hospital and late mortality were 7.0 % (n = 4) and 5.7 % (n = 3), respectively. One patient was reoperated on to close residual ventricular septal defect. Four patients were lost. Of the remaining 49 patients, the mean follow-up was 65 +/- 38 months (range 11 - 173 months). Actuarial survival was 97.4 +/- 2.5 %, 91 +/- 7 % and 72.8 +/- 17.1 % at 5, 10 and 14 years, respectively. At the latest follow-up, 35 (76.1 %) of the surviving patients presently have NYHA functional class I ( P < 0.01).
The overall survival of surgically treated adult patients with tetralogy of Fallot is acceptable. The greatest benefit of total correction at this age is the functional improvement.
评估成年期接受手术治疗的法洛四联症患者的长期结果，以确定手术矫正的实际益处。
1990年8月至2004年2月，57例年龄超过18岁的法洛四联症患者接受了根治手术。42例患者（73.7%）需要跨环补片。
住院死亡率和晚期死亡率分别为7.0%（n = 4）和5.7%（n = 3）。1例患者再次手术关闭残余室间隔缺损。4例患者失访。其余49例患者的平均随访时间为65±38个月（范围11 - 173个月）。5年、10年和14年的精算生存率分别为97.4±2.5%、91±7%和72.8±17.1%。在最近一次随访时，35例（76.1%）存活患者目前的心功能分级为纽约心脏协会（NYHA）I级（P < 0.01）。
成年法洛四联症手术治疗患者的总体生存率是可以接受的。在这个年龄段进行根治手术的最大益处是功能改善。
