用于治疗HIV感染的CCR5受体拮抗剂的发现：从先导化合物到先导物的研究 - Suppr

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超能文献

The discovery of CCR5 receptor antagonists for the treatment of HIV infection: hit-to-lead studies.

作者信息

Armour Duncan, de Groot Marcel J, Edwards Martin, Perros Manos, Price David A, Stammen Blanda L, Wood Anthony

机构信息

Pfizer Global Research and Development, Sandwich Laboratories, Ramsgate Road, Sandwich, Kent, CT13 9NJ, UK.

出版信息

ChemMedChem. 2006 Jul;1(7):706-9. doi: 10.1002/cmdc.200600031.

DOI:10.1002/cmdc.200600031

PMID:16902922

Abstract

摘要

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相似文献

The discovery of CCR5 receptor antagonists for the treatment of HIV infection: hit-to-lead studies.

ChemMedChem. 2006 Jul;1(7):706-9. doi: 10.1002/cmdc.200600031.

4,4-Disubstituted cyclohexylamine based CCR5 chemokine receptor antagonists as anti-HIV-1 agents.

Bioorg Med Chem Lett. 2009 Sep 1;19(17):4988-92. doi: 10.1016/j.bmcl.2009.07.074. Epub 2009 Jul 18.

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Bioorg Med Chem Lett. 2009 Feb 15;19(4):1075-9. doi: 10.1016/j.bmcl.2009.01.009. Epub 2009 Jan 10.

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