Unlü M, Ercan M T, Alanyali H, Akhan O, Bekdik C F
Department of Nuclear Medicine, Faculty of Medicine, Hacettepe University, Ankara, Turkey.
Nuklearmedizin. 1990 Feb;29(1):35-9.
Twenty-two women with stage II or III breast cancer were evaluated by SPECT to determine the number, size, three-dimensional localization and depth from skin surface of the internal mammary lymph nodes for accurate radiotherapy portal planning. The results were also compared with those of planar imaging (PI). Two-step injections of 99mTc-dextran were made under ultrasound guidance into the anterior sheath of the M. rectus abdominis first at the ablation side. 1.5 h thereafter an anterior planar view was obtained to evaluate cross drainage (13.6% was observed). Then, the second injection was done at the opposite side in the same manner. Planar and tomographic images were obtained 1.5 h after the second injection. Similar values were obtained for the depth from skin surface, distance from the midline and diameter of the lymph nodes with both PI and SPECT. The total number of nodes in 22 patients detected by SPECT was higher (138) than that from PI (129), the difference being statistically significant (0.005 greater than p greater than 0.0005).
对22例II期或III期乳腺癌女性患者进行了单光子发射计算机断层扫描（SPECT）评估，以确定内乳淋巴结的数量、大小、三维定位以及距皮肤表面的深度，从而进行精确的放射治疗野规划。并将结果与平面显像（PI）的结果进行比较。在超声引导下，分两步将99m锝标记的右旋糖酐注射到腹直肌前鞘，首先在切除侧注射。1.5小时后获取前位平面图像以评估交叉引流情况（观察到交叉引流率为13.6%）。然后，以相同方式在对侧进行第二次注射。第二次注射1.5小时后获取平面图像和断层图像。PI和SPECT在内乳淋巴结距皮肤表面的深度、距中线的距离以及直径方面得到了相似的值。SPECT检测到的22例患者的淋巴结总数（138个）高于PI检测到的数量（129个），差异具有统计学意义（0.005 > p > 0.0005）。
