Degenhardt P, Dieckow B, Mau H
Clinic of Pediatric Surgery, Otto-Heubner Center of Child and Adolescent Medicine, Charité Campus Virchow-Hospital, Humboldt University, Berlin, Germany.
Eur J Pediatr Surg. 2006 Jun;16(3):197-200. doi: 10.1055/s-2006-924285.
Lymphangiomas are rare congenital malformations of the lymphatic system. They typically appear within the first two years of life. They present as soft, indolent and benign tumors. As they have a tendency to grow in an infiltrating manner and rarely regress spontaneously, treatment may be necessary if the lymphangioma's location is functionally and cosmetically disturbing. Surgical therapy, which has been the treatment of choice so far, includes a risk of complications, depending on the location and extent of the tumor. Therefore alternative treatments such as sclerotherapy, especially with OK-432, have been developed. We present the case of a female baby with a huge macrocystic lymphangioma, extending over one half of the trunk, located intra- and extrathoracically, which was treated successfully by surgical resection and several intralesional injections of OK-432.
淋巴管瘤是淋巴系统罕见的先天性畸形。它们通常在出生后的头两年内出现。表现为柔软、无痛的良性肿瘤。由于它们有浸润性生长的倾向且很少自发消退，如果淋巴管瘤的位置在功能和美观上造成困扰，可能需要进行治疗。手术治疗是迄今为止的首选治疗方法，但根据肿瘤的位置和范围，存在并发症风险。因此，已开发出诸如硬化疗法等替代治疗方法，尤其是使用OK-432。我们报告了一例患有巨大囊状淋巴管瘤的女婴病例，该淋巴管瘤延伸至躯干的一半，位于胸腔内和胸腔外，通过手术切除和多次瘤内注射OK-432成功治愈。
