Zehe A, Ramirez A, Starostenko O
Biofizika. 2006 Jul-Aug;51(4):724-32.
For the modeling of erythrocyte rouleaux (linear cell aggregations), we propose an approximation procedure for the dipole moment in short cylinders, which contains the case of ellipsoidal bodies only as a first approximation. The method allows one to introduce corrections that are more representative for these particles. Depending on the number of erythrocytes forming an aggregation, i.e., on different but discrete measures of rouleaux lengths, the dielectrophoretic force is calculated and represented against the frequency of the applied a.c. field. As a result, frequency regions in the upper MHz range appear in which the strength and direction of DEP forces are different for different rouleaux sizes. This property is suitable for the detection and spatial separation of rouleaux populations of different length in blood samples by means of a microelectronic array.
对于红细胞缗钱状聚集(线性细胞聚集体)的建模,我们提出了一种针对短圆柱体中偶极矩的近似方法,该方法仅将椭球体情况作为一阶近似。该方法允许引入对这些粒子更具代表性的修正。根据形成聚集体的红细胞数量,即根据缗钱状长度的不同但离散的度量,计算介电泳力并将其表示为所施加交流电场频率的函数。结果,在兆赫兹以上范围出现了频率区域,其中不同缗钱状大小的介电泳力的强度和方向不同。这一特性适用于通过微电子阵列检测和空间分离血样中不同长度的缗钱状群体。