Erdmann Freidoon, Zandt Daniel, Auch Jürgen, Schütz Harald, Weiler Günter, Verhoff Marcel A
Institut für Rechtsmedizin der Universität Giessen.
Arch Kriminol. 2006 May-Jun;217(5-6):129-36.
The article describes critical investigations concerning the threshold value between endogenous and exogenous concentrations of gamma-hydroxybutyric acid (GHB/"liquid ecstasy") in human blood. The values of GHB in the blood samples of 50 blood donors and 50 postmortem cases were measured with a validated gas-chromatographic/mass-spectrometric procedure according to the guidelines of the GTFCh (Society of Toxicological and Forensic Chemistry). GHB-concentrations were found to range between 0.11 and 1.56 mg/L (mean value 0.54 mg/L/standard deviation 0.37 mg/L/coefficient of variation 68.4 %) in the donors' blood, and between 2.2 and 116 mg/L (mean value 32.4 mg/L/standard deviation 25.6 mg/L/coefficient of variation 79 %) in the postmortem samples, respectively.
这篇文章描述了关于人体血液中γ-羟基丁酸(GHB/“液体摇头丸”)内源性和外源性浓度阈值的关键研究。根据毒理和法医化学协会(GTFCh)的指南,采用经过验证的气相色谱/质谱法测量了50名献血者和50例尸检病例血样中的GHB值。发现献血者血液中GHB浓度范围为0.11至1.56毫克/升(平均值0.54毫克/升/标准差0.37毫克/升/变异系数68.4%),尸检样本中GHB浓度范围为2.2至116毫克/升(平均值32.4毫克/升/标准差25.6毫克/升/变异系数79%)。