Dai Hui-Fen, Gao Yuan, Yang Ming, Yu Chao-Hui, Gu Zhu-Ying, Chen Wei-Xing
Zhejiang University School of Medicine, Hangzhou 310003, China.
Hepatobiliary Pancreat Dis Int. 2006 Aug;5(3):406-8.
Hepatic veno-occlusive disease (VOD) or sinusoidal obstruction syndrome is associated with a high mortality because of its severity. Gymura segetum, a Chinese herbal medicine, is always used to cure injury and bleeding in rural areas in China. This study was undertaken to better understand VOD and its relations to the effect of Gymura segetum.
Between 2000 and 2002, two patients were admitted to our department because of VOD. Before admission, both of them had been injured and taken oral decoction of patent drug Gymura segetum. We analyzed the clinical manifestations, diagnosis and therapy of the two patients.
Pyrrolizidine in Panax notginseng was proved to induce VOD. The diagnosis of VOD depended on hepatic biopsy.
Gymura segetum can induce VOD. More attention should be paid to its unsuscepted side effects.
肝静脉闭塞病（VOD）或窦性阻塞综合征因其严重性而与高死亡率相关。白凤菜，一种中草药，在中国农村地区常用于治疗损伤和出血。本研究旨在更好地了解VOD及其与白凤菜作用的关系。
2000年至2002年期间，两名因VOD入住我科的患者。入院前，他们均受过伤并口服了白凤菜的专利药物汤剂。我们分析了这两名患者的临床表现、诊断和治疗情况。
证明三七中的吡咯里西啶可诱发VOD。VOD的诊断依赖于肝活检。
白凤菜可诱发VOD。应更多关注其未被察觉的副作用。
