Rubod Chrystèle, Houfflin Véronique, Belot Franck, Ardiet Emmanuel, Dufour Philippe, Subtil Damien, Deruelle Philippe
Clinique de Gynécologie-Obstétrique, Hôpital Jeanne de Flandre, CHRU de Lille, France.
Fetal Diagn Ther. 2006;21(5):410-3. doi: 10.1159/000093881.
Massive fetomaternal hemorrhage is an uncommon cause of chronic fetal anemia. Without treatment, hydrops fetalis can occur and progress toward death. In some cases, an early diagnosis can improve the management.
A patient was found to have a fetus with non-immune hydrops related to massive and early fetomaternal hemorrhage successfully treated with serial fetal intravascular transfusion. After the treatment, ultrasonographic signs of hydrops disappeared and the pregnancy resulted in a good fetal outcome. There was no need for neonatal transfusion. Neurological examination at 1 month post-natal was normal.
When massive fetomaternal hemorrhage is diagnosed early in the pregnancy, serial fetal intravascular transfusion may be an alternative to immediate delivery.
大量胎儿-母体出血是慢性胎儿贫血的罕见原因。未经治疗，可发生胎儿水肿并进展至死亡。在某些情况下，早期诊断可改善治疗。
一名患者被发现胎儿患有与大量早期胎儿-母体出血相关的非免疫性水肿，通过系列胎儿血管内输血成功治疗。治疗后，水肿的超声征象消失，妊娠获得良好的胎儿结局。无需新生儿输血。产后1个月的神经学检查正常。
当在妊娠早期诊断出大量胎儿-母体出血时，系列胎儿血管内输血可能是立即分娩的替代方法。
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