Montgomery L D, Belfort M A, Adam K
Department of Obstetrics and Gynecology, Baylor College of Medicine, Houston, TX 77030, USA.
Am J Obstet Gynecol. 1995 Jul;173(1):234-5. doi: 10.1016/0002-9378(95)90201-5.
One of the many causes of fetal hydrops is fetomaternal hemorrhage. This report presents a pregnancy with fetomaternal hemorrhage that was treated with serial combined intravascular and intraperitoneal fetal transfusions, resulting in a good outcome. A 26-year-old woman seen for ultrasonographic evaluation was found to have a fetus with hydrops fetalis. Fetal blood sampling demonstrated severe fetal anemia (hematocrit 16.4%). The initial Kleihauer-Betke test result on maternal blood was 6% fetal cells. The fetus was transfused five times over a 24-day period by means of a combined intravascular and intraperitoneal route. The fetus also received one platelet transfusion for thrombocytopenia. The pregnancy resulted in a good fetal outcome without the need for postpartum transfusion. This case represents successful treatment of fetal anemia and nonimmune hydrops with a serial combined intravascular and intraperitoneal transfusion technique.
胎儿水肿的众多病因之一是胎儿-母体出血。本报告介绍了一例因胎儿-母体出血而接受系列血管内和腹腔内联合胎儿输血治疗并取得良好结局的妊娠病例。一名因超声检查前来就诊的26岁女性被发现胎儿患有胎儿水肿。胎儿血液取样显示严重胎儿贫血（血细胞比容16.4%）。母体血液的初始克-贝试验结果为胎儿细胞6%。在24天内通过血管内和腹腔内联合途径对胎儿进行了5次输血。胎儿还因血小板减少接受了1次血小板输血。该妊娠获得了良好的胎儿结局，无需产后输血。本病例代表了采用系列血管内和腹腔内联合输血技术成功治疗胎儿贫血和非免疫性水肿。
