Khokhlov D T, Malyshev V V, Ogarkov P I
Lab Delo. 1990(1):25-7.
Current notions on the role of the thymol test (TT) in the diagnosis of viral hepatitis A are discussed. Changes in TT results over the course of the disease are presented, starting from the incubation period up to the second-third week; these values are compared to those of hepatitis A specific markers. The earliest TT shifts in hepatitis A are detectable already 15-18 days before the first clinical manifestations, when this parameter surpasses the upper threshold of the range of normal values. The incubation period TT values are 6.9-8.4 U S-H, those during the 3 weeks of the acute period are 9.1-9.7 U S-H. This test earlier reacts to liver inflammation than alanine aminotransferase (a hepatic enzyme) measurement, which fact recommends TT for active early detection of hepatitis A patients in epidemic foci in collective bodies. One more TT advantage over the detection of hepatitis A specific markers in epidemic foci is that it permits the diagnosis of hepatitis whatever its etiology.
本文讨论了麝香草酚试验（TT）在甲型病毒性肝炎诊断中作用的当前观点。展示了疾病过程中TT结果的变化，从潜伏期到第二至三周；这些值与甲型肝炎特异性标志物的值进行了比较。甲型肝炎最早的TT变化在首次临床表现前15 - 18天就可检测到，此时该参数超过正常范围的上限。潜伏期TT值为6.9 - 8.4 U S-H，急性期3周内的值为9.1 - 9.7 U S-H。该试验比丙氨酸转氨酶（一种肝酶）测量更早地对肝脏炎症作出反应，这一事实表明TT可用于在集体机构的流行地区早期主动检测甲型肝炎患者。在流行地区检测甲型肝炎方面，TT相对于检测甲型肝炎特异性标志物的另一个优势是，无论其病因如何，它都能诊断肝炎。
