Kim Mi Jung, Lindsey Derek P, Hannibal Matthew, Alamin Todd F
Department of Physical Medicine and Rehabilitation, Hanyang University, Seoul, Korea.
Spine (Phila Pa 1976). 2006 Aug 15;31(18):2079-84. doi: 10.1097/01.brs.0000231714.15876.76.
Ex vivo biomechanical study using osteoporotic cadaveric fractured vertebral bodies.
To investigate the behavior of fractured osteoporotic vertebral bodies treated with either vertebroplasty or kyphoplasty under repetitive loading conditions.
Vertebroplasty and kyphoplasty are newer alternatives for the treatment of osteoporotic vertebral fractures. Loading conditions that can lead to fractures treated with these methods will likely be encountered subsequently; as such, it is important to understand differences in the biomechanical behavior of the resultant constructs.
There were 7 pairs of osteoporotic T8 and T10 vertebral bodies cyclically loaded to produce a vertebral compression fracture. Of each pair, one was assigned to the kyphoplasty group and the other to the vertebroplasty group. After treatment, specimens were cyclically loaded to 100,000 cycles, between 20% and 70% of the predicted failure load.
Height was restored with kyphoplasty, but the vertebral bodies showed significant height loss during cyclic loading. Vertebroplasty specimens had higher compression stiffness and smaller height reduction.
Under repetitive loading conditions, fractured vertebral bodies treated with kyphoplasty were initially taller, but because of a progressive loss of height during loading, the resulting constructs were shorter after 100,000 cycles than those treated with vertebroplasty.
使用骨质疏松症尸体骨折椎体进行体外生物力学研究。
研究经椎体成形术或后凸成形术治疗的骨质疏松性骨折椎体在重复加载条件下的行为。
椎体成形术和后凸成形术是治疗骨质疏松性椎体骨折的新方法。随后可能会遇到导致这些方法治疗的骨折的加载条件;因此,了解所得结构生物力学行为的差异很重要。
7对骨质疏松性T8和T10椎体进行循环加载以产生椎体压缩骨折。每对中,一个分配到后凸成形术组,另一个分配到椎体成形术组。治疗后,将标本在预测破坏载荷的20%至70%之间循环加载至100,000次循环。
后凸成形术可恢复椎体高度,但椎体在循环加载过程中出现明显的高度丢失。椎体成形术标本具有更高的压缩刚度和更小的高度降低。
在重复加载条件下,经后凸成形术治疗的骨折椎体最初较高,但由于加载过程中高度逐渐丢失,100,000次循环后所得结构比经椎体成形术治疗的结构更短。