Herz Joachim
Department of Molecular Genetics, University of Texas Southwestern, Dallas, Texas 75390, USA.
Mol Cell. 2006 Aug;23(4):451-5. doi: 10.1016/j.molcel.2006.07.026.
The biosynthesis and export of LDL receptor-related proteins rely on specialized chaperones in the endoplasmic reticulum. Two recent papers in Molecular Cell by Fisher et al. (2006) and Lee et al. (2006) reveal a novel mechanism by which one of these chaperones, the receptor-associated protein RAP, accomplishes this task.
低密度脂蛋白受体相关蛋白的生物合成及输出依赖于内质网中的特定分子伴侣。费舍尔等人（2006年）以及李等人（2006年）近期发表于《分子细胞》杂志上的两篇论文揭示了一种新机制，通过该机制，其中一种分子伴侣——受体相关蛋白（RAP）得以完成此项任务。
