Paiva Adriana de Azevedo, Rondó Patrícia Helen de Carvalho, Gonçalves-Carvalho Cecília Maria Resende, Illison Vanessa Kristinne, Pereira Joilane Alves, Vaz-de-Lima Lourdes Rehder Andrade, de Oliveira Carmem Aparecida, Ueda Mirthes, Bergamaschi Denise Pimentel
Núcleo de Estudos e Pesquisas Epidemiológicas, Universidade Estadual da Paraíba, Campina Grande, Brasil.
Cad Saude Publica. 2006 Sep;22(9):1979-87. doi: 10.1590/s0102-311x2006000900029.
Vitamin A deficiency is a public health problem in the Northeast of Brazil. This study aimed to determine the prevalence of vitamin A deficiency and associated factors among preschool children in Teresina, Piauí, Brazil. We studied the serum retinol levels and socioeconomic and demographic characteristics of 631 children from 36 to 83 months of age. The statistical association between each of the above characteristics and serum retinol levels was investigated by univariate and multivariate linear regression analysis. Mean serum retinol was 1.21 mmol/L (95%CI: 1.17-1.25 micromol/L) and was independent of gender (p = 0.259). Prevalence of vitamin A deficiency (retinol < 0.69 micromol/L) was 15.4% (95%CI: 12.7-18.4), with a tendency to decrease with age. Acceptable but not adequate retinol levels (0.70 to 1.04 micromol/L) were observed in 29% of children (95%CI: 25.2-32.4). There were positive associations between retinol levels and age, income, vitamin A supplementation, and maternal schooling. Vitamin A deficiency appeared as a moderately serious public health problem, emphasizing the importance of strategies to combat this problem in the region.
维生素A缺乏是巴西东北部的一个公共卫生问题。本研究旨在确定巴西皮奥伊州特雷西纳市学龄前儿童维生素A缺乏的患病率及其相关因素。我们研究了631名年龄在36至83个月之间儿童的血清视黄醇水平以及社会经济和人口统计学特征。通过单变量和多变量线性回归分析研究上述各特征与血清视黄醇水平之间的统计关联。血清视黄醇平均水平为1.21 mmol/L(95%置信区间:1.17 - 1.25微摩尔/升),且与性别无关(p = 0.259)。维生素A缺乏(视黄醇<0.69微摩尔/升)的患病率为15.4%(95%置信区间:12.7 - 18.4),且有随年龄降低的趋势。29%的儿童(95%置信区间:25.2 - 32.4)血清视黄醇水平处于可接受但不充足的范围(0.70至1.04微摩尔/升)。视黄醇水平与年龄、收入、维生素A补充剂以及母亲受教育程度之间存在正相关。维生素A缺乏是一个中度严重的公共卫生问题,凸显了该地区应对这一问题策略的重要性。