Georgala Aspasia, Vekemans Marc, Husson Mireille, Meuleman Nathalie, Beguin Hugues, Nolard Nicole, Aoun Mickael
Infectious Disease Department, Jules Bordet Institute, Brussels, Belgium.
Acta Biomed. 2006;77 Suppl 2:5-9.
Zygomycosis is a highly aggressive infection observed in immunocompromised patients, such as those with haematological malignancies. The sites most frequently involved are the sinuses and the lungs. New diagnostic tools and new antifungal treatments are essential in order to diagnose early and treat efficiently infections due to moulds. We report a case of sinusitis due to Absidia corymbifera occurring during chemotherapy-induced bone marrow aplasia in a patient with acute leukaemia. The sinusitis was successfully treated with AmBisome, and surgical debridement.
接合菌病是一种在免疫功能低下患者中观察到的高度侵袭性感染,例如患有血液系统恶性肿瘤的患者。最常受累的部位是鼻窦和肺部。新的诊断工具和新型抗真菌治疗对于早期诊断和有效治疗霉菌感染至关重要。我们报告了一例急性白血病患者在化疗引起的骨髓再生障碍期间发生的由伞枝犁头霉引起的鼻窦炎病例。该鼻窦炎通过两性霉素B脂质体和手术清创成功治愈。