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异基因骨髓移植后由伞枝犁头霉引起的侵袭性皮肤毛霉病。

Invasive cutaneous mucormycosis caused by Absidia corymbifera after allogeneic bone marrow transplantation.

作者信息

Jantunen E, Kolho E, Ruutu P, Koukila-Kähkölä P, Virolainen M, Juvonen E, Volin L

机构信息

Department of Medicine, Kuopio University Hospital, Finland.

出版信息

Bone Marrow Transplant. 1996 Jul;18(1):229-30.

PMID:8832023
Abstract

Mucormycotic infections caused by fungi of the families Rhizopus, Mucor or Absidia are rare and usually associated with diabetes or immunosuppression. We describe a patient with invasive necrotizing cutaneous mucormycosis caused by Absidia corymbifera shortly after allogeneic BMT. The infection was successfully treated with surgical debridement and liposomal amphotericin B for 6 weeks. Recognition of these rare infections requires a high index of suspicion. These patients should be evaluated with tissue biopsy and cultures and treated without delay.

摘要

由根霉属、毛霉属或犁头霉属真菌引起的毛霉病感染较为罕见,通常与糖尿病或免疫抑制有关。我们描述了一名在异基因骨髓移植后不久发生由伞枝犁头霉引起的侵袭性坏死性皮肤毛霉病的患者。通过手术清创和脂质体两性霉素B治疗6周后,感染得到成功控制。认识到这些罕见感染需要高度的怀疑指数。应对这些患者进行组织活检和培养评估,并立即进行治疗。

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