Takayama K, Okada J, Miura M
Department of Physiology, Gunma University School of Medicine, Maebashi, Japan.
Neurosci Lett. 1990 Feb 16;109(3):241-6. doi: 10.1016/0304-3940(90)90001-p.
Projections from the central amygdaloid nucleus (ACE) to the ventrolateral nucleus (VLN) of the medulla oblongata were studied using the wheat germ agglutinin-horseradish peroxidase (WGA-HRP) method. WGA-HRP was injected into the rostral VLN, where a pressor response associated with bradycardiac and apneustic responses was elicited by microinjection of glutamate, and into the caudal VLN, where a depressor response associated with bradycardiac and apneustic responses was elicited. In both experiments, HRP-labeled cells were found in the ACE. These results suggest that the ACE may send direct projections to the VLN and may play a role in cardiovascular and/or respiratory control mechanisms.
采用小麦胚凝集素-辣根过氧化物酶（WGA-HRP）法研究了中央杏仁核（ACE）向延髓腹外侧核（VLN）的投射。将WGA-HRP注入延髓腹外侧核头端，微量注射谷氨酸可在此处诱发与心动过缓和呼吸暂停反应相关的升压反应；同时也将WGA-HRP注入延髓腹外侧核尾端，在此处可诱发与心动过缓和呼吸暂停反应相关的降压反应。在这两个实验中，均在中央杏仁核中发现了HRP标记的细胞。这些结果表明，中央杏仁核可能直接向延髓腹外侧核投射，并可能在心血管和/或呼吸控制机制中发挥作用。
