Roh Mi Ryung, Chung Hye-Jin, Cho Young-Hun, Chung Kee Yang
Department of Dermatology and Cutaneous Biology Research Institute, Yonsei University College of Medicine, Yonsei University, Seoul, Korea.
J Dermatol. 2006 Aug;33(8):574-6. doi: 10.1111/j.1346-8138.2006.00124.x.
Hypertrichosis lanuginosa acquisita (HLA) is an unusual condition which is characterized by subtle and progressive development of multiple, long, thin, unmedullated hairs ("lanugo hairs") distributed preferentially on the face. Most cases are associated with malignant tumors or non-malignant condition such as porphyria cutanea tarda, AIDS, anorexia nervosa, thyrotoxicosis, or secondary to topical or systemic drugs (e.g. cyclosporine, phenytoin, diazoxide, minoxidil). We have recently experienced a rare case of hypertrichosis lanuginosa acquisita associated with autoimmune hepatitis. To our best knowledge, this is the first report of hypertrichosis lanuginosa acquisita associated with autoimmune hepatitis. Our observation expands the spectrum of diseases associated with this uncommon disorder.
获得性胎毛增多症（HLA）是一种罕见病症，其特征为多根细长、无髓质的毛发（“胎毛”）逐渐细微地生长，且优先分布于面部。大多数病例与恶性肿瘤或非恶性疾病相关，如迟发性皮肤卟啉病、艾滋病、神经性厌食症、甲状腺毒症，或继发于局部或全身性药物（如环孢素、苯妥英、二氮嗪、米诺地尔）。我们最近遇到了一例罕见的与自身免疫性肝炎相关的获得性胎毛增多症病例。据我们所知，这是首例与自身免疫性肝炎相关的获得性胎毛增多症报告。我们的观察扩展了与这种罕见病症相关的疾病谱。
