Alhola Paula, Polo-Kantola Päivi, Erkkola Risto, Portin Raija
Department of Psychology, Sleep Research Unit, University of Turku, Turku, Finland.
Neurology. 2006 Aug 22;67(4):706-9. doi: 10.1212/01.wnl.0000230135.10179.86.
The authors evaluated the effect of long-term hormone therapy (HT) on cognition in 60 postmenopausal women (aged 53 to 72 years) in a single-blind, 6-year follow-up study. The subjects were divided into three groups: non-HT users, continuous HT users, and irregular HT users. Measures of verbal and visuomotor skills, verbal and visual memory, and attention were used. All women had well-maintained cognitive performance. Long-term HT did not affect cognition, either for better or for worse.
作者在一项单盲、为期6年的随访研究中,评估了长期激素疗法(HT)对60名绝经后女性(年龄53至72岁)认知功能的影响。受试者被分为三组:非HT使用者、持续HT使用者和不规律HT使用者。采用了语言和视觉运动技能、语言和视觉记忆以及注意力的测量方法。所有女性的认知表现均保持良好。长期HT对认知功能没有影响,无论是变好还是变差。