Matas Carla Gentile, de Juan Kleber Ramos, Nakano Renata Agnello
Universidade Federal de São Paulo, Escola Paulista de Medicina.
Pro Fono. 2006 May-Aug;18(2):171-6. doi: 10.1590/s0104-56872006000200006.
Middle and late latency auditory evoked potentials.
to verify the occurrence of middle and late latency auditory evoked potentials disorders in adults with Acquired Immunodeficiency Syndrome (AIDS).
Middle and late latency auditory evoked potentials of 8 individuals with AIDS, with ages ranging from 10 to 51 years, with normal hearing, or with sensoryneural hearing losses up to moderate, and normal results in the Auditory Brainstem Response, comparing the results with the responses obtained for a control group which was composed by 25 individuals, with ages ranging from 19 to 24 years, with no hearing complaints and with normal hearing and normal results in the Auditory Brainstem Response.
The Pa wave latency and amplitude averages in the C3/A2 and C4/A1 modalities, and the average of the P300 wave were analyzed. No significant differences were observed in the Pa wave amplitude and latency averages between the groups, although a non-statistically significant increase was observed in the latency and a decrease in the amplitude of such wave for the research group in the C3/A2 modality. The latency of the P300 wave was significantly longer to the left for the research group. It was also observed a longer latency to the right, although this was not statistically significant.
Adult individuals with AIDS do not present alterations in the middle latency auditory evoked potential and do present alterations in the cognitive potential, indicating a disorder in the cortical regions of the auditory pathway and a deficit in the cognitive processing of auditory information for this population. Such findings stress the importance of a careful investigation of the auditory function of individuals with AIDS, thus favoring the therapeutic planning.
中潜伏期和晚潜伏期听觉诱发电位。
验证获得性免疫缺陷综合征(艾滋病)成人患者中潜伏期和晚潜伏期听觉诱发电位障碍的发生情况。
对8名年龄在10至51岁之间、听力正常或伴有中度以下感音神经性听力损失且听觉脑干反应结果正常的艾滋病患者进行中潜伏期和晚潜伏期听觉诱发电位检测,并将结果与由25名年龄在19至24岁之间、无听力主诉、听力正常且听觉脑干反应结果正常的个体组成的对照组的反应结果进行比较。
分析了C3/A2和C4/A1模式下的Pa波潜伏期和波幅平均值以及P300波的平均值。两组之间在Pa波波幅和潜伏期平均值方面未观察到显著差异,尽管研究组在C3/A2模式下该波的潜伏期有非统计学意义的增加且波幅有所下降。研究组左侧P300波的潜伏期明显更长。右侧潜伏期也较长,尽管这在统计学上不显著。
艾滋病成年个体在中潜伏期听觉诱发电位方面未出现改变,但在认知电位方面出现改变,这表明该人群听觉通路的皮质区域存在障碍以及听觉信息的认知处理存在缺陷。这些发现强调了仔细调查艾滋病患者听觉功能的重要性,从而有利于治疗计划的制定。