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颞下-耳前入路在颞下及鼻咽部肿瘤治疗中的应用

Subtemporal-preauricular approach in the management of infratemporal and nasopharyngeal tumours.

作者信息

Llorente José L, Nazar Gonzalo, Cabanillas Rubén, Fernández de León Ramón, Suárez Carlos

机构信息

Department of Otolaryngology and Skull Base Unit, Hospital Central de Asturias, Spain.

出版信息

J Otolaryngol. 2006 Jun;35(3):173-9.

Abstract

OBJECTIVES

To evaluate the indication, advantages, and results of the subtemporal-preauricular approach in the resection of tumours arising in the infratemporal fossa and related structures of the lateral cranial base.

DESIGN

Retrospective analysis of patients treated by the subtemporal-preauricular approach to resect nasopharyngeal and infratemporal tumours.

SETTING

Tertiary hospital.

METHODS

Forty patients with lateral skull base lesions were managed with the subtemporal-preauricular approach. There were 19 benign lesions and 21 malignant tumours, the most common being nasopharyngeal carcinomas, juvenile angiofibromas, and adenoid-cystic carcinomas. Most of the tumours were at an advanced stage, with skull base involvement in 13 benign tumours and in 14 malignant ones.

RESULTS

Major complications occurred in 6 (14%) patients, and there were 2 (5%) postoperative deaths. All 19 patients with benign tumours are alive, although 5 of them (26%) presented with residual or recurrent disease. The 5-year estimated survival rate of the 21 patients with malignant neoplasms was 39%.

CONCLUSIONS

The subtemporal-preauricular approach is a safe and versatile approach to the infratemporal fossa and neighbouring areas of the lateral cranial base, offering satisfactory oncologic results in the absence of intracranial involvement.

摘要

目的

评估颞下-耳前入路在切除颞下窝及颅底外侧相关结构肿瘤中的适应证、优势及效果。

设计

对采用颞下-耳前入路切除鼻咽部及颞下肿瘤的患者进行回顾性分析。

地点

三级医院。

方法

40例颅底外侧病变患者采用颞下-耳前入路治疗。其中良性病变19例,恶性肿瘤21例,最常见的是鼻咽癌、青少年血管纤维瘤和腺样囊性癌。大多数肿瘤处于晚期,13例良性肿瘤和14例恶性肿瘤侵犯颅底。

结果

6例(14%)患者发生主要并发症,2例(5%)术后死亡。19例良性肿瘤患者均存活,其中5例(26%)出现残留或复发疾病。21例恶性肿瘤患者的5年估计生存率为39%。

结论

颞下-耳前入路是一种安全且通用的治疗颞下窝及颅底外侧相邻区域的方法,在无颅内侵犯的情况下可提供满意的肿瘤学效果。

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