Schuckit Marc A
VA San Diego Healthcare System, San Diego, CA, USA.
Addiction. 2006 Sep;101 Suppl 1:76-88. doi: 10.1111/j.1360-0443.2006.01592.x.
To review information relevant to the question of whether substance-induced mental disorders exist and their implications.
This paper utilized a systematic review of manuscripts published in the English language since approximately 1970 dealing with comorbid psychiatric and substance use disorders.
The results of any specific study depended on the definitions of comorbidity, the methods of operationalizing diagnostic criteria, the interview and protocol invoked several additional methodological issues. The results generally support the conclusion that substance use mental disorders exist, especially regarding stimulant or cannabinoid-induced psychoses, substance-induced mood disorders, as well as substance-induced anxiety conditions.
The material reviewed indicates that induced disorders are prevalent enough to contribute significantly to rates of comorbidity between substance use disorders and psychiatric conditions, and that their recognition has important treatment implications. The current literature review underscores the heterogeneous nature of comorbidity.
回顾与物质所致精神障碍是否存在及其影响相关的信息。
本文对自1970年以来发表的英文手稿进行了系统综述，这些手稿涉及共病的精神障碍和物质使用障碍。
任何特定研究的结果取决于共病的定义、诊断标准的操作方法、访谈和方案，还引发了其他几个方法学问题。结果总体上支持物质使用精神障碍存在的结论，特别是关于兴奋剂或大麻素所致精神病、物质所致心境障碍以及物质所致焦虑状态。
所审查的资料表明，所致障碍普遍存在，足以对物质使用障碍和精神疾病之间的共病率产生重大影响，并且对其的认识具有重要的治疗意义。当前的文献综述强调了共病的异质性。
