Hughes Fiona M, Kavanagh Dara, Barry Mary, Owens Anthony, MacErlaine Donal P, Malone Dermot E
Department of Radiology, St Vincent's University Hospital, Dublin 4, Ireland.
Abdom Imaging. 2007 May-Jun;32(3):398-402. doi: 10.1007/s00261-006-9062-7. Epub 2006 Aug 25.
To assess the sensitivity and specificity of computed tomography (CT) in the diagnosis of aortoenteric fistula (AEF) and to determine the most accurate CT signs of the disease.
Hospital records were reviewed over a 20-year period. Twenty-three patients in whom a final diagnosis of AEF was made at laparotomy or autopsy were identified. Ten of these had CT performed. Twelve control cases were also collected. The 22 cases, (10 cases of AEF and 12 controls), were reviewed retrospectively by two independent readers, who were blinded to the clinical features and outcome. Each case was examined for six specific radiological findings. The outcome of other adopted investigative modalities was also examined.
The presence of peri-aortic ectopic gas (>2 weeks following surgery) in the context of gastrointestinal (GI) blood loss was 100% specific for AEF. If AEF was considered to be present where signs of peri-aortic infection were present in a patient with GI bleeding, CT had an overall specificity of 100% (95% confidence interval = 1.0-1.0) and sensitivity of 50%.
CT can rule in the diagnosis of AEF but cannot rule it out. CT is recommended as the first-line investigation in a stable patient with suspected AEF.
评估计算机断层扫描(CT)在诊断主动脉肠瘘(AEF)中的敏感性和特异性,并确定该疾病最准确的CT征象。
回顾20年期间的医院记录。确定了23例在剖腹手术或尸检时最终诊断为AEF的患者。其中10例进行了CT检查。还收集了12例对照病例。由两名独立的阅片者对这22例病例(10例AEF和12例对照)进行回顾性分析,阅片者对临床特征和结果不知情。对每个病例检查六个特定的影像学表现。还检查了其他采用的检查方法的结果。
在胃肠道(GI)失血的情况下,主动脉周围异位气体(手术后>2周)的存在对AEF具有100%的特异性。如果在胃肠道出血患者中存在主动脉周围感染迹象时考虑存在AEF,CT的总体特异性为100%(95%置信区间 = 1.0 - 1.0),敏感性为50%。
CT可以确诊AEF,但不能排除该诊断。对于疑似AEF的稳定患者,建议将CT作为一线检查方法。