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用于稳定颈椎泪滴形骨折的手术固定结构的生物力学评估

Biomechanical evaluation of surgical constructs for stabilization of cervical teardrop fractures.

作者信息

Ianuzzi Allyson, Zambrano Isidoro, Tataria Jigar, Ameerally Azeema, Agulnick Marc, Goodwin Jesse S Little, Stephen Mark, Khalsa Partap S

机构信息

Department of Biomedical Engineering, Stony Brook University, HSC T18-030, Stony Brook, NY 11794, USA.

出版信息

Spine J. 2006 Sep-Oct;6(5):514-23. doi: 10.1016/j.spinee.2005.12.001. Epub 2006 Jul 11.

Abstract

BACKGROUND CONTEXT

Cervical flexion teardrop fractures (CFTF) are highly unstable injuries, and the optimal internal fixation construct is not always clearly indicated.

PURPOSE

The purpose of the current study was to determine whether the type of fixation construct (anterior, posterior, or combined) or number of joint levels involved in fixation (one or two) affected the relative stability of a CFTF injury at C5-C6.

STUDY DESIGN/SETTING: Human cadaveric cervical spine specimens were mechanically tested under displacement control in the intact state and after creation of CFTF at C5-C6 with stabilization using five different instrumentation constructs. Joint stiffness and intervertebral translation of the constructs were compared with the intact state and normalized (instrumented/intact) to assess relative differences across the five constructs.

METHODS

Spine specimens were mechanically tested in the intact state during flexion, extension, lateral bending, and axial rotation. CFTF was created at C5-C6 by creating an osteotomy at C5 and transecting the posterior ligaments and intervertebral disc. Specimens were tested with anterior, posterior, and combined single-level constructs (C5-C6). Then, a corpectomy was performed at C5, and specimens were retested with the two-level constructs (C4-C6; anterior and anterior-posterior). Joint stiffness and intervertebral translations were computed.

RESULTS

All five fixation constructs resulted in joint stability that was as good as or better than that of the intact specimens. Relative stiffness of the constructs differed depending upon the motion type considered, though the two-level anterior-posterior construct typically provided the greatest stability. Intervertebral translation along the major axis was reduced the most for both of the combined instrumentation systems, although there were few changes in total intervertebral translation across the five constructs.

CONCLUSIONS

All five constructs restored stability comparable to that of the intact specimens. The significance of the relative differences in constructs for the in vivo spine is unclear and warrants further clinical investigation.

摘要

背景

颈椎屈曲泪滴形骨折(CFTF)是高度不稳定的损伤,最佳的内固定结构并不总是明确的。

目的

本研究的目的是确定固定结构类型(前路、后路或联合)或固定涉及的关节节段数(一个或两个)是否会影响C5-C6节段CFTF损伤的相对稳定性。

研究设计/设置:使用五种不同的内固定结构对人尸体颈椎标本在完整状态下以及在C5-C6节段造成CFTF损伤并进行稳定处理后,在位移控制下进行力学测试。将各结构的关节刚度和椎间平移与完整状态进行比较并进行归一化处理(内固定/完整),以评估五种结构之间的相对差异。

方法

对脊柱标本在完整状态下进行前屈、后伸、侧屈和轴向旋转时的力学测试。通过在C5处进行截骨并切断后韧带和椎间盘,在C5-C6节段造成CFTF损伤。对标本使用前路、后路和联合单节段结构(C5-C6)进行测试。然后,在C5处进行椎体次全切除术,再使用双节段结构(C4-C6;前路和前后联合)对标本进行重新测试。计算关节刚度和椎间平移。

结果

所有五种固定结构均能使关节稳定性与完整标本相当或更好。各结构的相对刚度因所考虑的运动类型而异,尽管双节段前后联合结构通常提供最大的稳定性。两种联合内固定系统沿主轴的椎间平移减少最多,尽管五种结构的总椎间平移变化不大。

结论

所有五种结构均能恢复与完整标本相当的稳定性。各结构相对差异对体内脊柱的意义尚不清楚,值得进一步临床研究。

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