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与骨软化症相关的严重脊柱后凸侧弯

Severe kyphoscoliosis associated with osteomalacia.

作者信息

Motosuneya Takao, Asazuma Takashi, Yasuoka Hiroki, Tsuji Takashi, Fujikawa Kyosuke

机构信息

Department of Orthopaedic Surgery, National Defense Medical College, 3-2, Namiki, Tokorozawa, Saitama, 359-8513, Japan.

出版信息

Spine J. 2006 Sep-Oct;6(5):587-90. doi: 10.1016/j.spinee.2006.01.008.

Abstract

BACKGROUND CONTEXT

Kyphoscoliosis is one of the most frequent complications of osteomalacia, which only rarely results in severe deformity requiring surgery. To the best of our knowledge, there has been only one previous report of a spinal deformity as a complication of osteomalacia that was sufficiently severe so as to require surgical treatment.

PURPOSE

To report here the case of a 27-year-old woman who experienced back pain of gradual onset accompanied by progressive scoliosis resulting in severe dyspnea.

STUDY DESIGN

A case report.

METHODS

She was diagnosed with hypophosphatemic osteomalacia and secondary hyperparathyroidism. She underwent posterior surgical correction and fusion from Th4-L1 using the ISOLA spinal system.

RESULTS

At the last follow-up (3 year and 9 months postoperatively), her body balance was good and the dyspnea had disappeared. Plain radiographs demonstrated no loss of correction and also showed no evidence of instrumentation failure.

CONCLUSIONS

We present a unique instance of a young woman with severe kyphoscoliosis who underwent posterior surgical correction/fusion with spinal instrumentation.

摘要

背景

脊柱后凸侧弯是骨软化症最常见的并发症之一,极少导致严重畸形而需手术治疗。据我们所知,此前仅有一份关于脊柱畸形作为骨软化症并发症且严重到需要手术治疗的报告。

目的

本文报告一例27岁女性病例,该患者逐渐出现背痛并伴有进行性脊柱侧弯,导致严重呼吸困难。

研究设计

病例报告。

方法

她被诊断为低磷性骨软化症和继发性甲状旁腺功能亢进。她接受了使用ISOLA脊柱系统从胸4至腰1的后路手术矫正及融合术。

结果

在最后一次随访(术后3年9个月)时,她身体平衡良好,呼吸困难消失。X线平片显示矫正无丢失,也无内固定失败的迹象。

结论

我们展示了一例年轻女性严重脊柱后凸侧弯的独特病例,该患者接受了后路手术矫正/融合及脊柱内固定术。

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