Castillo Pablo R, Miller David A, Meschia James F
Department of Neurology, University of Minnesota, Minneapolis VA Medical Center, Minneapolis, MN, USA.
Neurol Clin. 2006 Nov;24(4):807-20. doi: 10.1016/j.ncl.2006.05.004.
At the time of this publication, the fast examination time, wide availability, lack of contraindications, and high accuracy for detecting hemorrhage make NCCT the diagnostic study of choice for initial evaluation of patients who have preoperative stroke. NCCT also has a role in excluding patients who will not benefit from IV thrombolysis, including those who have ICH and patients who have ASPECTS less than 7 or ischemic signs exceeding one third of the MCA territory. Because optimal selection of inpatients who have acute stroke mandates not just brain tissue data but also information about the aortic arch, cervical and intracranial vasculature, and cerebral hemodynamics, additional imaging with multimodal CT technology can, in one scanning session, depicts early ischemic changes, demonstrates hypoperfusion/ischemic penumbra, and locates the vascular lesion. When combined with the clinical scenario, the information provided by CT often is sufficient to help clinicians decide on the appropriate treatment, especially determining eligibility for thrombolysis. The rapidly evolving field of neuroradiology will provide a newer armamentarium in the near future. Although MRI can provide more precise information, it is more time consuming and currently should be considered the method of choice for follow-up imaging, rather than initial imaging, in patients who have perioperative stroke.
在本出版物发表之时,检查时间短、广泛可用、无禁忌证以及检测出血的准确性高,使得非增强计算机断层扫描(NCCT)成为术前中风患者初始评估的首选诊断研究方法。NCCT在排除那些无法从静脉溶栓中获益的患者方面也发挥着作用,包括那些患有脑出血(ICH)的患者以及脑梗死溶栓治疗选择量表(ASPECTS)评分低于7分或缺血迹象超过大脑中动脉(MCA)供血区域三分之一的患者。由于对急性中风住院患者的最佳选择不仅需要脑组织数据,还需要有关主动脉弓、颈部和颅内血管以及脑血流动力学的信息,多模态CT技术的额外成像可以在一次扫描过程中描绘早期缺血性变化、显示灌注不足/缺血半暗带并定位血管病变。结合临床情况,CT提供的信息通常足以帮助临床医生决定合适的治疗方法,尤其是确定溶栓的 eligibility。神经放射学快速发展的领域在不久的将来将提供更新的手段。尽管磁共振成像(MRI)可以提供更精确的信息,但它耗时更长,目前对于围手术期中风患者,应被视为随访成像而非初始成像的首选方法。