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[用于螺旋式投照的精密调强放疗和影像引导放疗的螺旋断层放射治疗系统:最新进展与临床应用]

[The TomoTherapy Hi.Art System for sophisticated IMRT and IGRT with helical delivery: Recent developments and clinical applications].

作者信息

Tomsej M

机构信息

Unité d'imagerie moléculaire et radiothérapie expérimentale (IMRE), université catholique de Louvain, 10/4752, avenue Hippocrate, 1200 Bruxelles, Belgique.

出版信息

Cancer Radiother. 2006 Sep;10(5):288-95. doi: 10.1016/j.canrad.2006.07.006. Epub 2006 Aug 28.

Abstract

The advent of 3D conformal radiotherapy and intensity modulated radiation therapy (IMRT) make possible the dose optimization to complex target volumes close to sane organs at risk. IMRT's introduction of numerous small radiation fields inherently increases delivery inaccuracies. As a consequence, the use of IMRT without precise localization of the tumor and sensitive structures, at both the planning and delivery stages, and the absence of continuous verification represent the most significant challenges to the implementation of IMRT in routine clinical use. Intensity modulated (or not) conformal radiotherapy delivery requires better precision in the definition of treatment volume, frequently if necessary. Helical tomotherapy has been designed to use CT imaging technology to plan, deliver, and verify that the delivery has been carried out as planned. The image-guided and intensity modulations processes of helical tomotherapy that enable this goal are described.

摘要

三维适形放疗和调强放射治疗(IMRT)的出现,使得对靠近敏感危及器官的复杂靶区进行剂量优化成为可能。IMRT引入众多小辐射野,本质上增加了照射的不准确性。因此,在计划和实施阶段,若未对肿瘤及敏感结构进行精确的定位,且缺乏连续验证,使用IMRT便是在常规临床应用中实施IMRT面临的最重大挑战。调强(或非调强)适形放疗的实施通常需要在必要时更精确地定义治疗体积。螺旋断层放疗旨在利用CT成像技术进行计划、实施,并验证照射是否按计划进行。本文描述了螺旋断层放疗实现这一目标的图像引导和调强过程。

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