Del Priore Lucian V
Department of Ophthalmology, Columbia University, New York, New York, USA.
Am J Ophthalmol. 2006 Sep;142(3):435-40. doi: 10.1016/j.ajo.2006.04.019.
To measure the wrinkling periodicity (peak-to-peak or trough-to-trough distance) for epiretinal membranes and contraction-induced choroidal folds, and use this data to infer differences in the elastic properties of the retina and choroid, respectively.
Retrospective case review.
Forty eyes were identified with epiretinal membranes (33 eyes) or contraction-induced choroidal folds (seven eyes). Digital red-free photographs were used to determine the average peak-to-peak distance between adjacent folds of retina or choroid using commercially available software.
The average peak-to-peak spacing was considerably larger for contraction-induced choroidal folds vs retinal folds caused by epiretinal membranes (278.2 +/- 62.2 vs 82.2 +/- 7.66 microm, respectively; P = .0001). There was no statistically significant correlation between the peak-to-peak distance and patient age for the epiretinal membrane group (P = .25) or the choroidal folds group, although the age range of patients within the later group was narrow.
Epiretinal membranes and contraction-induced choroidal folds are two examples of wrinkling of biologic tissue under tangential stress. The larger peak-to-peak spacing for choroidal folds vs retinal folds demonstrates that the choroid is considerably stiffer than the retina under mechanical deformations.
测量视网膜前膜和收缩性脉络膜皱褶的皱纹周期（峰-峰或谷-谷距离），并利用这些数据分别推断视网膜和脉络膜弹性特性的差异。
回顾性病例分析。
确定40只眼中存在视网膜前膜（33只眼）或收缩性脉络膜皱褶（7只眼）。使用数码无赤光照片，通过商用软件测定视网膜或脉络膜相邻皱褶之间的平均峰-峰距离。
收缩性脉络膜皱褶的平均峰-峰间距显著大于视网膜前膜引起的视网膜皱褶（分别为278.2±62.2与82.2±7.66微米；P = 0.0001）。视网膜前膜组或脉络膜皱褶组的峰-峰距离与患者年龄之间无统计学显著相关性（P = 0.25），尽管后一组患者的年龄范围较窄。
视网膜前膜和收缩性脉络膜皱褶是切向应力下生物组织起皱的两个例子。脉络膜皱褶的峰-峰间距大于视网膜皱褶，表明在机械变形下脉络膜比视网膜硬得多。
