Büyükyavuz Behçet Ilker, Adiloglu Ali Kudret, Onal Süleyman, Cubukcu Saadettin Ender, Cetin Hasan
Department of Pediatric Surgery, Suleyman Dermirel University Medical Faculty, Isparta, Turkey.
Jpn J Infect Dis. 2006 Aug;59(4):213-5.
This study was conducted to determine whether the hospital devices and materials used for the examination and treatment of patients play a role in the outbreaks of infection in hospitals. Environmental sampling was performed to find the possible sources of septicemia at the neonatal intensive care unit (NICU). Environmental sampling results and blood culture records from the outbreak areas were compared to determine if they had any relationship with each other. Semisolid and solid samples were compared with liquid samples for positive cultures using a chi-square test. Statistical significance was accepted at P<0.05. The results showed that liquid sources were more frequent media for infectious agents (OR, 8.75; chi-square, 0.0278). The most common cultured microorganisms were coagulase negative Staphylococcus and Klebsiella pneumoniae, which were responsible for septicemias at NICU. There were strong relationships between environmental culture results and the agents responsible for the outbreak of septicemia at the NICU. The formula heater at the pediatrics clinic also revealed the same microorganisms with the blood cultures of 3 patients in the same clinic. Although there are matches between the environmental sampling and blood culture records in our study, there is a need for further studies. We conclude that moist areas and liquid environments must be regularly checked for pathogen microorganisms. Instead of using heated water to sterilize infant formula, dry air sterilization should be used. Liquid media like oxygen reservoir solution and antiseptic solutions must be checked for contamination and should be changed periodically.
本研究旨在确定用于患者检查和治疗的医院设备及材料是否在医院感染暴发中起作用。在新生儿重症监护病房（NICU）进行环境采样，以寻找败血症的可能来源。将暴发区域的环境采样结果与血培养记录进行比较，以确定它们之间是否存在任何关系。使用卡方检验比较半固体和固体样本与液体样本的阳性培养结果。P<0.05时接受统计学显著性。结果表明，液体来源是感染病原体更常见的媒介（比值比，8.75；卡方值，0.0278）。最常见的培养微生物是凝固酶阴性葡萄球菌和肺炎克雷伯菌，它们是NICU败血症的致病菌。环境培养结果与NICU败血症暴发的致病菌之间存在密切关系。儿科诊所的配方奶加热器也显示出与同一诊所3名患者血培养相同的微生物。尽管我们的研究中环境采样和血培养记录之间存在匹配，但仍需要进一步研究。我们得出结论，必须定期检查潮湿区域和液体环境中的病原微生物。应使用干空气灭菌而非热水对婴儿配方奶进行灭菌。必须检查储氧溶液和防腐剂溶液等液体介质是否受到污染，并应定期更换。
