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颅内血管母细胞瘤:一项机构经验。

Intracranial hemangioblastomas: an institutional experience.

作者信息

Dwarakanath Srinivas, Suri Ashish, Sharma Bhavani Shanker, Mehta Veer Singh

机构信息

Department of Neurosurgery, Neurosciences Center, All India Institute of Medical Sciences, New Delhi, 110029, India.

出版信息

Neurol India. 2006 Sep;54(3):276-8. doi: 10.4103/0028-3886.27152.

Abstract

BACKGROUND AND AIMS

We present our Institutional experience with intracranial hemangioblastomas.

SETTINGS AND DESIGN

A retrospective study.

MATERIALS AND METHODS

This study included all patients of intracranial hemangioblastomas admitted in our institution over a period of 11 years from January 1992 through June 2003.

RESULTS

There were a total of 69 patients (45 males and 24 females). The average age at presentation was 34.5 years. The tumor was located in the cerebellar hemispheres, vermian and brainstem regions in 42 (60%) patients, 19 (28%) patients and 8 (12%) patients, respectively. Hydrocephalus was seen in 48 (69%) patients. Thirty-three patients underwent CSF diversion procedures prior to surgery on the tumor. All except one underwent definitive surgery. The mortality was 8 (11%). Sixty eight patients underwent surgery on the tumor. The follow-up ranged from 1 month to 11 years. Fifteen patients developed recurrent lesions.

CONCLUSION

Lifelong surveillance is necessary in cases with hemangioblastomas to identify recurrences especially in those patients having VHL syndrome.

摘要

背景与目的

我们介绍我们机构颅内血管母细胞瘤的治疗经验。

设置与设计

一项回顾性研究。

材料与方法

本研究纳入了1992年1月至2003年6月期间在我们机构收治的所有颅内血管母细胞瘤患者。

结果

共有69例患者(45例男性和24例女性)。就诊时的平均年龄为34.5岁。肿瘤分别位于小脑半球、蚓部和脑干区域的患者有42例(60%)、19例(28%)和8例(12%)。48例(69%)患者出现脑积水。33例患者在肿瘤手术前接受了脑脊液分流手术。除1例患者外,所有患者均接受了根治性手术。死亡率为8例(11%)。68例患者接受了肿瘤手术。随访时间为1个月至11年。15例患者出现复发病变。

结论

对于血管母细胞瘤患者,尤其是患有VHL综合征的患者,终身监测对于识别复发是必要的。

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