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Morphological and quantitative aspects of the development of cytoplasmic granules in concanavalin A-stimulated normal human lymphocytes.

作者信息

McGirl A, Shea G, Melinn M, McLaughlin H

机构信息

Department of Pathology, University College Dublin, Ireland.

出版信息

J Leukoc Biol. 1990 Jun;47(6):514-8. doi: 10.1002/jlb.47.6.514.

DOI:10.1002/jlb.47.6.514
PMID:1693648
Abstract

We have studied normal human lymphocytes stimulated by concanavalin A to determine the rate and extent of development of cytoplasmic granules. Morphological studies on stimulated lymphocytes were undertaken at the light and electron microscopic level. The percentage of T lymphocytes bearing different CD antigens (CD3, CD4, and CD8) that also contained cytoplasmic granules was also assessed. Granules were identified in a high percentage of lymphocytes bearing each of the three CD markers studied.

摘要

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