Khetsuriani N, Holman R C, Lamonte-Fowlkes A C, Selik R M, Anderson L J
Respiratory and Enteric Viruses Branch, Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Atlanta, GA 30333, USA.
Epidemiol Infect. 2007 May;135(4):583-91. doi: 10.1017/S0950268806007163. Epub 2006 Aug 29.
The United States national mortality statistics and HIV/AIDS surveillance data were analysed to determine trends in encephalitis-associated deaths and to assess the impact of HIV infection on those deaths during 1979-1998, a period when ICD-9 codes were used for coding deaths in the United States. A total of 25125 encephalitis deaths were reported; 4779 of them (19%) had concurrent HIV infection. Overall encephalitis death rates remained stable, but they increased for groups where HIV infection was common and declined or remained unchanged for others. For persons without HIV infection, the rates declined in all demographic groups. Encephalitis deaths in HIV-infected persons followed general trends for HIV deaths in the United States. The rates in the HIV-infected population were several hundred- to thousand-fold higher than in the HIV-uninfected population. HIV infection was largely responsible for the lack of overall decline in the considerable mortality associated with encephalitis in the United States during 1979-1998.
分析了美国国家死亡率统计数据和艾滋病毒/艾滋病监测数据，以确定与脑炎相关的死亡趋势，并评估1979年至1998年期间艾滋病毒感染对这些死亡的影响，这一时期美国使用国际疾病分类第九版（ICD-9）编码死亡情况。共报告了25125例脑炎死亡病例；其中4779例（19%）同时感染了艾滋病毒。总体脑炎死亡率保持稳定，但在艾滋病毒感染常见的人群中有所上升，而在其他人群中则下降或保持不变。对于未感染艾滋病毒的人，所有人口群体的死亡率都有所下降。艾滋病毒感染者的脑炎死亡情况与美国艾滋病毒死亡的总体趋势一致。艾滋病毒感染人群的死亡率比未感染艾滋病毒人群高出数百至数千倍。艾滋病毒感染在很大程度上导致了1979年至1998年期间美国与脑炎相关的相当高的死亡率缺乏总体下降。
