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[家鼠(小家鼠)1号染色体上均匀染色区双插入现象的出现原因]

[The causes of appearance of a double insertion of homogeneously staining regions in the chromosome 1 of house mouse (Mus musculus musculus)].

作者信息

Agul'nik S I, Borodin P M, Gorlov I P, Ladygina T Iu, Pak S D

出版信息

Genetika. 1990 Mar;26(3):570-2.

PMID:1693902
Abstract

A high resolution analysis of G-band pattern of normal and aberrant chromosome 1 bearing two linked insertions of homogeneously staining regions (HSRs) in the house mouse (Mus musculus musculus) reveals an inverted pattern of the euchromatic region between the HSRs. On the basis of this analysis, a hypothesis on the causes for appearance of the aberrant chromosome was put forward: the double insertion is a result of inversion of the chromosome 1 of Mus musculus domesticus bearing a single long insertion. The proximal breakpoint is localized inside the HSR and the distal one--between subbands E3 and E4. From the point of view of these data, new symbols for the aberrations are proposed: Ls (HSR, 1C5) 1Icg--for the proximal insertion, Is(HSR, 1D)21cg--for the distal one, In (1) 1Icg--for the inverted region, including the bands D, E1-E3 and the insertion Is(HSR 1D)21cg.

摘要

对家鼠(小家鼠)中携带两个同源染色区(HSRs)连锁插入的正常和异常1号染色体的G带模式进行高分辨率分析,结果显示HSRs之间常染色质区域呈现倒转模式。基于此分析,提出了关于异常染色体出现原因的假说:双重插入是小家鼠1号染色体发生倒转并携带单个长插入片段的结果。近端断点位于HSR内部,远端断点位于E3和E4亚带之间。根据这些数据,提出了异常的新符号:Ls(HSR,1C5)1Icg表示近端插入,Is(HSR,1D)21cg表示远端插入,In(1)1Icg表示倒转区域,包括D、E1 - E3带以及插入片段Is(HSR 1D)21cg。

相似文献

1
[The causes of appearance of a double insertion of homogeneously staining regions in the chromosome 1 of house mouse (Mus musculus musculus)].[家鼠(小家鼠)1号染色体上均匀染色区双插入现象的出现原因]
Genetika. 1990 Mar;26(3):570-2.
2
The origin of a double insertion of homogeneously staining regions in the house mouse (Mus musculus musculus).
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Double insertion of homogeneously staining regions in chromosome 1 of wild Mus musculus musculus: effects on chromosome pairing and recombination.野生小家鼠染色体1中均匀染色区的双重插入:对染色体配对和重组的影响。
J Hered. 1990 Mar-Apr;81(2):91-5.
4
[Synapsis and recombination of chromosomes in the house mouse homozygous for the double inversion of the homogeneously stained regions in chromosome 1].
Genetika. 1990 Apr;26(4):657-63.
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[Variability of chromosome 1 with HSR insertions in natural and synanthropous populations of house mouse Mus musculus L. 1758].[1758年小家鼠(Mus musculus L.)自然种群和伴人种群中含均一染色区插入的1号染色体的变异性]
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[A new variant of chromosome 1 in the house mouse].
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[Effect of double insertion of homogeneously stained regions in chromosome 1 of the house mouse on recombination frequency].[小家鼠1号染色体上均匀染色区的双重插入对重组频率的影响]
Genetika. 1989 Feb;25(2):220-5.