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[兰道-克莱夫纳综合征]

[Landau-Kleffner syndrome].

作者信息

Elliger T J, Trott G E, Hoffmeyer O, Nissen G

机构信息

Klinik und Poliklinik, Universitäts-Nervenklinik Würzburg.

出版信息

Fortschr Neurol Psychiatr. 1990 Apr;58(4):125-36. doi: 10.1055/s-2007-1001176.

Abstract

In 1957, Landau and Kleffner reported six cases of a "syndrome of acquired aphasia with convulsive disorder". Since this first report more than 130 cases with acquired language disabilities with EEG-abnormalities have been described. Comprehension of language is primarily affected, spike discharges are predominantly found in temporal regions. Facultative symptoms are epileptic seizures and psychiatric disorders. The paper gives a review of the literature describing the clinical manifestations, the therapeutic procedure, the prognosis and the etiological factors of this syndrome, which is even listed in the last version of the ICD-10 and the International Classification of Epilepsies and Epileptic Syndromes.

摘要

1957年,兰道和克莱夫纳报告了6例“获得性失语伴惊厥障碍综合征”。自首次报告以来,已有130多例伴有脑电图异常的获得性语言障碍病例被描述。语言理解能力受到主要影响,棘波放电主要出现在颞叶区域。兼有的症状是癫痫发作和精神障碍。本文对描述该综合征临床表现、治疗方法、预后及病因的文献进行了综述,该综合征甚至被列入ICD - 10最新版本以及《癫痫及癫痫综合征国际分类》中。

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