Kaufman Melissa R, DeMarco Romano T, Pope John C, Scarpero Harriette M, Adams Mark C, Trusler Lisa A, Brock John W
Division of Pediatric Urology, Department of Urology, Vanderbilt University, Vanderbilt Children's Hospital, 2200 Children's Way, Nashville, TN 37232, USA.
J Urol. 2006 Oct;176(4 Pt 2):1835-7. doi: 10.1016/j.juro.2006.03.125.
In the pediatric population urodynamic evaluation for nonneurological causes has been previously reported as a low yield endeavor when considering patients with a primary diagnosis of dysfunctional voiding. We evaluated the rate of clinically significant urodynamic findings that would drive therapeutic intervention for a spectrum of urological disorders in pediatric patients without neurological deficit in whom initial conventional management had failed.
We retrospectively reviewed the charts of patients who had undergone urodynamics in the last 7 years. Patients with known neurological deficits were excluded.
A total of 805 pediatric urodynamic evaluations were performed from December 1997 to July 2004 at our institution, including 89 in patients with no known neurological diagnosis and charts available for review. Of the urodynamic studies 33 (37.1%) were reported as normal and 56 patients (62.9%) had clinically significant discoveries. Storage phase abnormalities were the predominant finding in 37 patients (66.1%), including uninhibited detrusor contractions in 31 (55.4%). Emptying phase abnormalities were less common (19 patients or 33.9%). There was no difference in the percent of patients with positive urodynamics findings depending on sex.
In our analysis evaluation of all recent urodynamics performed at a single institution revealed a high rate of pathological findings in patients with various nonneurological diagnoses.
先前有报道称,对于以功能性排尿障碍为主要诊断的儿科患者,进行非神经源性病因的尿动力学评估时,发现有价值结果的几率较低。我们评估了一系列儿科泌尿系统疾病患者在初始常规治疗失败且无神经功能缺损的情况下,能促使进行治疗干预的具有临床意义的尿动力学检查结果的发生率。
我们回顾性分析了过去7年中接受尿动力学检查的患者病历。排除已知有神经功能缺损的患者。
1997年12月至2004年7月,我们机构共进行了805例儿科尿动力学评估,其中89例患者无已知神经学诊断且病历可供查阅。在这些尿动力学检查中,33例(37.1%)报告为正常,56例(62.9%)有具有临床意义的发现。储尿期异常是37例(66.1%)患者的主要发现,其中31例(55.4%)为逼尿肌无抑制性收缩。排尿期异常较少见(19例患者,占33.9%)。根据性别分组,尿动力学检查结果为阳性的患者比例无差异。
在我们的分析中,对单一机构近期进行的所有尿动力学检查评估显示,各种非神经学诊断的患者中病理检查结果的发生率较高。