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与联合化疗相关的掌跖红斑

Palmar-plantar erythema associated with combination chemotherapy.

作者信息

Pagliuca A, Kaczmarski R, Mufti G J

机构信息

Academic Department of Haematological Medicine, King's College Hospital, Denmark Hill, London, UK.

出版信息

Postgrad Med J. 1990 Mar;66(773):242-3. doi: 10.1136/pgmj.66.773.242.

DOI:10.1136/pgmj.66.773.242
PMID:1694580
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2429475/
Abstract

We report three cases of a distinctive palmar-plantar erythema associated with the treatment of non-Hodgkin's lymphoma and acute myeloid leukaemia. The rash is characterized by a painful, sharply demarcated, intense erythema of the palms and/or soles followed by bulla formation, desquamation and healing. The eruption is self limiting in nature and did not adversely affect prognosis. Treatment need be neither altered nor stopped; only symptomatic measures are required.

摘要

我们报告了三例与非霍奇金淋巴瘤和急性髓细胞白血病治疗相关的独特的掌跖红斑病例。皮疹的特征是手掌和/或脚底出现疼痛、边界清晰、强烈的红斑,随后形成水疱、脱皮并愈合。这种皮疹本质上是自限性的,对预后没有不利影响。治疗无需改变或停止;仅需要采取对症措施。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d63/2429475/2ea3097a1354/postmedj00159-0084-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d63/2429475/2ea3097a1354/postmedj00159-0084-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d63/2429475/2ea3097a1354/postmedj00159-0084-a.jpg

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Palmar-plantar erythema associated with combination chemotherapy.与联合化疗相关的掌跖红斑
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本文引用的文献

1
Erythema and desquamation after high-dose methotrexate.大剂量甲氨蝶呤后的红斑和脱屑。
Ann Intern Med. 1983 May;98(5 Pt 1):611-2. doi: 10.7326/0003-4819-98-5-611.
2
Chemotherapy-associated palmar-plantar erythrodysesthesia syndrome.化疗相关的手足红斑感觉异常综合征
Ann Intern Med. 1984 Dec;101(6):798-9. doi: 10.7326/0003-4819-101-6-798.
3
Raynaud's phenomenon: a common toxicity after combination chemotherapy for testicular cancer.雷诺现象:睾丸癌联合化疗后一种常见的毒性反应。
Ann Intern Med. 1981 Sep;95(3):288-92. doi: 10.7326/0003-4819-95-3-288.
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Cutaneous toxicity of bleomycin therapy.博来霉素治疗的皮肤毒性
Arch Dermatol. 1973 Apr;107(4):553-5.
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Palmar-plantar erythrodysesthesia and cytarabine.
Ann Intern Med. 1985 Apr;102(4):556. doi: 10.7326/0003-4819-102-4-556_1.
6
Painful red hands: a side-effect of leukaemia therapy.疼痛的红手:白血病治疗的一种副作用。
Br J Dermatol. 1988 Aug;119(2):249-53. doi: 10.1111/j.1365-2133.1988.tb03208.x.
7
Toxic erythema of palms and soles associated with high-dose mercaptopurine chemotherapy.与高剂量巯嘌呤化疗相关的掌跖毒性红斑
Arch Dermatol. 1986 Dec;122(12):1413-4.
8
MACOP-B chemotherapy for the treatment of diffuse large-cell lymphoma.MACOP-B化疗方案用于治疗弥漫性大细胞淋巴瘤。
Ann Intern Med. 1985 May;102(5):596-602. doi: 10.7326/0003-4819-102-5-596.