Biological phenotypes and genetic research on schizophrenia.
作者信息
Weinberger Daniel R
机构信息
Clinical Brain Disorders Branch, Intramural Research Program, National Institute of Mental Health, 10 Center Drive, Bethesda, MD 20892, USA.
出版信息
World Psychiatry. 2002 Feb;1(1):2-6.
Abstract
摘要
相似文献
1
Biological phenotypes and genetic research on schizophrenia.精神分裂症的生物学表型与遗传学研究
World Psychiatry. 2002 Feb;1(1):2-6.
2
Alternative phenotypes for the complex genetics of schizophrenia.精神分裂症复杂遗传学的替代表型。
Biol Psychiatry. 1999 Mar 1;45(5):551-8. doi: 10.1016/s0006-3223(98)00321-7.
3
Phenotype evaluation and genomewide linkage study of clinical variables in schizophrenia.精神分裂症临床变量的表型评估和全基因组连锁研究。
Am J Med Genet B Neuropsychiatr Genet. 2011 Dec;156B(8):929-40. doi: 10.1002/ajmg.b.31240. Epub 2011 Sep 29.
4
The genetics of cognitive impairment in schizophrenia: a phenomic perspective.精神分裂症认知障碍的遗传学：表型观点。
Trends Cogn Sci. 2011 Sep;15(9):428-35. doi: 10.1016/j.tics.2011.07.002. Epub 2011 Aug 2.
5
Elementary phenotypes in the neurobiological and genetic study of schizophrenia.精神分裂症神经生物学和遗传学研究中的基本表型
Biol Psychiatry. 1999 Jul 1;46(1):8-18. doi: 10.1016/s0006-3223(99)00085-2.
6
Neurocognitive allied phenotypes for schizophrenia and bipolar disorder.精神分裂症和双相情感障碍的神经认知相关表型。
Schizophr Bull. 2008 Jul;34(4):743-59. doi: 10.1093/schbul/sbn027. Epub 2008 Apr 29.
7
Functional connectivity measures as schizophrenia intermediate phenotypes: advances, limitations, and future directions.作为精神分裂症中间表型的功能连接性测量：进展、局限性及未来方向
Curr Opin Neurobiol. 2016 Feb;36:7-14. doi: 10.1016/j.conb.2015.07.008. Epub 2015 Aug 11.
8
The use of polygenic risk scores to identify phenotypes associated with genetic risk of schizophrenia: Systematic review.多基因风险评分在识别与精神分裂症遗传风险相关表型中的应用：系统评价。
Schizophr Res. 2018 Jul;197:2-8. doi: 10.1016/j.schres.2017.10.037. Epub 2017 Nov 10.
9
The DRD2 rs1076560 polymorphism and schizophrenia-related intermediate phenotypes: A systematic review and meta-analysis.DRD2 rs1076560 多态性与精神分裂症相关中间表型：系统评价和荟萃分析。
Neurosci Biobehav Rev. 2017 Mar;74(Pt A):214-224. doi: 10.1016/j.neubiorev.2017.01.006. Epub 2017 Jan 16.
10
Intermediate phenotypes in schizophrenia: a selective review.精神分裂症的中间型表型：选择性综述。
Dialogues Clin Neurosci. 2005;7(2):165-79. doi: 10.31887/DCNS.2005.7.2/gpreston.
引用本文的文献
1
Tumor necrosis factor-α (TNF-α) -308G >a promoter polymorphism (rs1800629) promotes Asians in susceptibility to Plasmodium falciparum severe malaria: A meta-analysis.肿瘤坏死因子-α（TNF-α）-308G > a 启动子多态性（rs1800629）增加亚洲人感染恶性疟原虫严重疟疾的易感性：一项荟萃分析。
PLoS Negl Trop Dis. 2023 Nov 1;17(11):e0011735. doi: 10.1371/journal.pntd.0011735. eCollection 2023 Nov.
2
Gender effects on brain changes in early-onset psychosis.性别对早发性精神病大脑变化的影响。
Eur Child Adolesc Psychiatry. 2015 Oct;24(10):1193-205. doi: 10.1007/s00787-014-0669-x. Epub 2015 Jan 15.
3
Neurobiological markers of illness onset in psychosis and schizophrenia: The search for a moving target.精神分裂症和精神病性障碍发病的神经生物学标记物：追寻移动的目标。
Neuropsychol Rev. 2009 Sep;19(3):385-98. doi: 10.1007/s11065-009-9114-1.
4
Anhedonia as a phenotype for the Val158Met COMT polymorphism in relatives of patients with schizophrenia.快感缺乏作为精神分裂症患者亲属中Val158Met COMT基因多态性的一种表型。
J Abnorm Psychol. 2008 Nov;117(4):788-98. doi: 10.1037/a0013745.
5
Dysfunctional connectivity in schizophrenia.精神分裂症中的功能连接障碍。
World Psychiatry. 2002 Jun;1(2):66-71.
6
Developing therapeutics for schizophrenia and other psychotic disorders.开发针对精神分裂症和其他精神障碍的治疗方法。
NeuroRx. 2005 Oct;2(4):579-89. doi: 10.1602/neurorx.2.4.579.
本文引用的文献
1
A functional polymorphism in the COMT gene and performance on a test of prefrontal cognition.儿茶酚-O-甲基转移酶（COMT）基因的功能性多态性与前额叶认知测试表现
Am J Psychiatry. 2002 Apr;159(4):652-4. doi: 10.1176/appi.ajp.159.4.652.
2
Prefrontal neurons and the genetics of schizophrenia.前额叶神经元与精神分裂症的遗传学
Biol Psychiatry. 2001 Dec 1;50(11):825-44. doi: 10.1016/s0006-3223(01)01252-5.
3
Relative risk for cognitive impairments in siblings of patients with schizophrenia.精神分裂症患者兄弟姐妹认知障碍的相对风险。
Biol Psychiatry. 2001 Jul 15;50(2):98-107. doi: 10.1016/s0006-3223(01)01133-7.
4
5
Effect of COMT Val108/158 Met genotype on frontal lobe function and risk for schizophrenia.儿茶酚-O-甲基转移酶Val108/158 Met基因型对额叶功能及精神分裂症风险的影响。
Proc Natl Acad Sci U S A. 2001 Jun 5;98(12):6917-22. doi: 10.1073/pnas.111134598. Epub 2001 May 29.
6
An association between reduced interhemispheric EEG coherence in the temporal lobe and genetic risk for schizophrenia.
Schizophr Res. 2001 Apr 15;49(1-2):129-43. doi: 10.1016/s0920-9964(00)00128-6.
7
The inheritance of neuropsychological dysfunction in twins discordant for schizophrenia.精神分裂症不一致的双胞胎中神经心理功能障碍的遗传情况。
Am J Hum Genet. 2000 Aug;67(2):369-82. doi: 10.1086/303006. Epub 2000 Jul 3.
8
Family-based linkage disequilibrium mapping using SNP marker haplotypes: application to a potential locus for schizophrenia at chromosome 22q11.
Mol Psychiatry. 2000 Jan;5(1):77-84. doi: 10.1038/sj.mp.4000638.
9
Lack of normal pattern of cerebral asymmetry in familial schizophrenic patients and their relatives--The Maudsley Family Study.家族性精神分裂症患者及其亲属大脑不对称正常模式的缺失——莫兹利家族研究
Schizophr Res. 1999 Nov 30;40(2):111-20. doi: 10.1016/s0920-9964(99)00143-7.
10
Thalamic and amygdala-hippocampal volume reductions in first-degree relatives of patients with schizophrenia: an MRI-based morphometric analysis.精神分裂症患者一级亲属的丘脑及杏仁核-海马体积减小：基于磁共振成像的形态学分析
Biol Psychiatry. 1999 Oct 1;46(7):941-54. doi: 10.1016/s0006-3223(99)00075-x.
Zotero 插件