Pardowitz I, Ehrhardt W, Neuhoff V
Max Planck-Institute for Experimental Medicine, Göttingen, Federal Republic of Germany.
Electrophoresis. 1990 May;11(5):400-6. doi: 10.1002/elps.1150110509.
The process of quantitative densitometry is analyzed with methods developed in information theory. It is shown that the steps involved in densitometry, e.g. gel staining, mechanical, optical and electronic processing, as well as all the steps of data processing, can be viewed as communication channels. The factors affecting both the relevant and irrelevant part of the total information passed through these channels are discussed in the consistent frame provided by information theory. This view leads to a unifying context for analyzing the performance of quantitative densitometers.
