洞察力与认知障碍：对轻度认知障碍和阿尔茨海默病患者生活质量报告的影响。
Insight and cognitive impairment: effects on quality-of-life reports from mild cognitive impairment and Alzheimer's disease patients.
作者信息
Ready Rebecca E, Ott Brian R, Grace Janet
机构信息
University of Massachusetts, Department of Psychology, Amherst 01003, USA.
出版信息
Am J Alzheimers Dis Other Demen. 2006 Aug-Sep;21(4):242-8. doi: 10.1177/1533317506290589.
Abstract
This study follows previous work to determine the effect of patient insight and cognitive impairment on the reliability and validity of self-reported quality of life (QOL) from patients diagnosed with Alzheimer's disease (AD) and mild cognitive impairment (MCI). AD and MCI patients (N = 68) and their caregivers participated. Patients with impaired insight provided QOL ratings that were less reliable than those provided by patients with better insight. Patient-caregiver agreement for. QOL reports was used as an index of validity. Neither better insight nor lesser cognitive impairment suggested better agreement. Thus, even when patient insight is intact, patient reports are unlikely to agree with caregiver reports. Patient and caregiver reports about patient QOL may represent 2 unique, yet potentially valid, perspectives.
摘要
本研究延续先前工作，以确定患者洞察力和认知障碍对阿尔茨海默病（AD）和轻度认知障碍（MCI）患者自我报告的生活质量（QOL）的可靠性和有效性的影响。AD和MCI患者（N = 68）及其照料者参与了研究。洞察力受损的患者提供的生活质量评分比洞察力较好的患者提供的评分可靠性更低。患者与照料者对生活质量报告的一致性被用作有效性指标。更好的洞察力和较轻的认知障碍均未表明有更好的一致性。因此，即使患者洞察力完好，患者报告也不太可能与照料者报告一致。患者和照料者关于患者生活质量的报告可能代表两种独特但可能有效的观点。
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