Kocan R, Lapatra S, Gregg J, Winton J, Hershberger P
School of Aquatic and Fishery Sciences, University of Washington, Seattle, WA 98358, USA.
J Fish Dis. 2006 Sep;29(9):521-7. doi: 10.1111/j.1365-2761.2006.00745.x.
Swimming stamina, measured as time-to-fatigue, was reduced by approximately two-thirds in rainbow trout experimentally infected with Ichthyophonus. Intensity of Ichthyophonus infection was most severe in cardiac muscle but multiple organs were infected to a lesser extent. The mean heart weight of infected fish was 40% greater than that of uninfected fish, the result of parasite biomass, infiltration of immune cells and fibrotic (granuloma) tissue surrounding the parasite. Diminished swimming stamina is hypothesized to be due to cardiac failure resulting from the combination of parasite-damaged heart muscle and low myocardial oxygen supply during sustained aerobic exercise. Loss of stamina in Ichthyophonus-infected salmonids could explain the poor performance previously reported for wild Chinook and sockeye salmon stocks during their spawning migration.
以疲劳时间衡量的游泳耐力，在实验感染了鱼怪虫的虹鳟鱼中降低了约三分之二。鱼怪虫感染强度在心肌中最为严重，但多个器官也有较轻程度的感染。受感染鱼的平均心脏重量比未受感染鱼重40%，这是寄生虫生物量、免疫细胞浸润以及寄生虫周围纤维化（肉芽肿）组织的结果。游泳耐力下降被推测是由于寄生虫损伤的心肌与持续有氧运动期间低心肌氧供应相结合导致的心力衰竭。感染鱼怪虫的鲑科鱼类耐力丧失可以解释先前报道的野生奇努克鲑和红大马哈鱼种群在产卵洄游期间表现不佳的原因。
