Chitkara Denesh K, Di Lorenzo Carlo
UNC Center for Functional GI and Motility Disorders, Division of Pediatric Gastroenterology, University of North Carolina School of Medicine, Chapel Hill, North Carolina, USA.
Curr Opin Pharmacol. 2006 Dec;6(6):536-40. doi: 10.1016/j.coph.2006.06.008. Epub 2006 Sep 1.
Functional gastrointestinal disorders are among the most common medical problems in pediatrics. However, only a few well-designed trials have evaluated the efficacy and safety of treatments in these conditions. Data obtained from studies conducted in adults are often utilized to tailor treatment to children with functional gastrointestinal disorders. This practice might lead to substantial medication under- or over-dosing, or use of drugs for an incorrect indication.
功能性胃肠疾病是儿科最常见的医学问题之一。然而，只有少数设计良好的试验评估了这些病症治疗的有效性和安全性。从成人研究中获得的数据常被用于为患有功能性胃肠疾病的儿童量身定制治疗方案。这种做法可能导致药物大量不足或过量服用，或药物使用适应症错误。
