Tuimala R J, Kauppila A J, Haalahti J
Obstet Gynecol. 1975 Sep;46(3):275-8.
The circulating level of ACTH (by radioimmunoassay) and cortisol (by competitive protein binding) were determined at 1- to 2-hour intervals during spontaneous labor (N=8) and induced labor (N=28) and after delivery. There were no differences in ACTH levels between primiparous and multiparous women. The primiparous women displayed a higher level of cortisol throughout labor than the multiparous women, but not after delivery. After spontaneous onset of labor, ACTH levels were always lower than after elective induction of labor, while there were no differences in the levels of cortisol. The hypertensive complications of pregnancy did not affect the secretion of ACTH. In normal pregnancy the rise of cortisol during labor and after delivery was significant, but it was not significant in the group of patients with hypertensive complications.
在自然分娩(N = 8)和引产(N = 28)期间以及分娩后,每隔1至2小时测定一次促肾上腺皮质激素(通过放射免疫测定)和皮质醇(通过竞争性蛋白结合)的循环水平。初产妇和经产妇的促肾上腺皮质激素水平没有差异。在整个分娩过程中,初产妇的皮质醇水平高于经产妇,但分娩后并非如此。自然发动分娩后,促肾上腺皮质激素水平总是低于择期引产,而皮质醇水平没有差异。妊娠高血压并发症不影响促肾上腺皮质激素的分泌。在正常妊娠中,分娩期间和分娩后皮质醇的升高是显著的,但在患有高血压并发症的患者组中并不显著。