Higo Takami, Mawatari Masaaki, Shigematsu Masamori, Hotokebuchi Takao
Department of Orthopaedic Surgery, Saga University, Saga-City, Japan.
J Arthroplasty. 2006 Sep;21(6):852-6. doi: 10.1016/j.arth.2005.10.016.
The purpose of this study was to determine the incidence of heterotopic ossifications (HOs) after total hip arthroplasty in Japanese patients and the predisposing factors associated with this condition. One thousand hips of 885 patients undergoing cementless total hip arthroplasties were examined with respect to the incidence and severity of HO; the data analysis was conducted by using the univariate and multivariate methods. The overall incidence of HO was 5.2%, with severe HO in 0.9% of the patients. A significant increase in the frequency of HO was observed in patients with ankylosed hips (odds ratio, 11.1; 95% confidence interval, 2.5-49.9), hypertrophic osteoarthritis (odds ratio, 2.7; 95% confidence interval, 1.2-5.9), and with a particular type of prosthesis used (ceramic-on-ceramic vs ceramic-on-polyethylene) (odds ratio, 2.5; 95% confidence interval, 1.3-4.8).
本研究的目的是确定日本患者全髋关节置换术后异位骨化(HO)的发生率以及与该病症相关的诱发因素。对885例行非骨水泥型全髋关节置换术患者的1000髋进行了HO发生率和严重程度的检查;采用单因素和多因素方法进行数据分析。HO的总体发生率为5.2%,0.9%的患者发生严重HO。在髋关节强直患者(优势比,11.1;95%置信区间,2.5 - 49.9)、肥厚性骨关节炎患者(优势比,2.7;95%置信区间,1.2 - 5.9)以及使用特定类型假体(陶瓷对陶瓷与陶瓷对聚乙烯)的患者中,观察到HO发生率显著增加(优势比,2.5;95%置信区间,1.3 - 4.8)。