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乙型血友病患者延迟性脾破裂的非手术治疗

Nonoperative management of delayed splenic rupture in a patient with hemophilia B.

作者信息

Terry N Elizabeth, Boswell William C

机构信息

Department of Surgery, Division of Pediatric Surgery, Memorial Health University Medical Center, Mercer University School of Medicine, Savannah, GA 31404, USA.

出版信息

J Pediatr Surg. 2006 Sep;41(9):1607-9. doi: 10.1016/j.jpedsurg.2006.05.061.

DOI:10.1016/j.jpedsurg.2006.05.061
PMID:16952601
Abstract

Nonoperative management of splenic lacerations has become the standard of care in hemodynamically stable patients. The decision to manage a patient nonoperatively is much more difficult when the patient has a known bleeding disorder. There are a few case reports in the literature describing nonoperative management of splenic trauma in children with hemophilia A (factor VIII deficiency), but only one case report of a patient with hemophilia B (factor IX deficiency) and a splenic laceration successfully managed nonoperatively. We present the case of a 13-year-old boy who presented with a grade 4 splenic laceration, acute blood loss anemia, and hypotension that was managed nonoperatively.

摘要

对于血流动力学稳定的患者,脾破裂的非手术治疗已成为标准治疗方法。当患者已知有出血性疾病时,决定对其进行非手术治疗要困难得多。文献中有几例病例报告描述了对患有甲型血友病(因子VIII缺乏症)的儿童脾外伤进行非手术治疗的情况,但仅有一例关于乙型血友病(因子IX缺乏症)患者脾破裂成功进行非手术治疗的病例报告。我们报告一例13岁男孩的病例,该男孩出现4级脾破裂、急性失血性贫血和低血压,经非手术治疗。

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