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认知障碍对中风后3年机构化率的影响。

Influence of cognitive impairment on the institutionalisation rate 3 years after a stroke.

作者信息

Pasquini M, Leys D, Rousseaux M, Pasquier F, Hénon H

机构信息

Department of Neurology (Stroke Unit), Lille University Hospital, Lille, France.

出版信息

J Neurol Neurosurg Psychiatry. 2007 Jan;78(1):56-9. doi: 10.1136/jnnp.2006.102533. Epub 2006 Sep 4.

Abstract

BACKGROUND AND PURPOSE

Pre-existing cognitive decline and new-onset dementia are common in patients with stroke, but their influence on institutionalisation rates is unknown.

OBJECTIVE

To evaluate the influence of cognitive impairment on the institutionalisation rate 3 years after a stroke.

DESIGN

(1) The previous cognitive state of 192 consecutive patients with stroke living at home before the stroke (with the Informant Questionnaire on COgnitive Decline in the Elderly (IQCODE)), (2) new-onset dementia occurring within 3 years and (3) institutionalisation rates within 3 years in the 165 patients who were discharged alive after the acute stage were prospectively evaluated.

RESULTS

Independent predictors of institutionalisation over a 3-year period that were available at admission were age (adjusted odds ratio (adjOR) for 1-year increase = 1.08; 95% confidence interval (CI) 1.03 to 1.15), severity of the neurological deficit (adjOR for 1-point increase in Orgogozo score = 0.97; 95% CI 0.96 to 0.99) and severity of cognitive impairment (adjOR for 1-point increase in IQCODE score = 1.03; 95% CI 1 to 1.06). Factors associated with institutionalisation at 3 years that were present at admission or occurred during the follow-up were age (adjOR for 1-year increase = 1.17; 95% CI 1.07 to 1.27) and any (pre-existing or new) dementia (adjOR = 5.85; 95% CI 1.59 to 21.59), but not the severity of the deficit of the neurological deficit.

CONCLUSION

Age and cognitive impairment are more important predictors of institutionalisation 3 years after a stroke than the severity of the physical disability.

摘要

背景与目的

既往存在的认知功能减退和新发痴呆在卒中患者中很常见,但它们对机构化率的影响尚不清楚。

目的

评估认知障碍对卒中后3年机构化率的影响。

设计

(1)前瞻性评估192例在家中卒中前连续的卒中患者的既往认知状态(使用老年人认知功能减退知情者问卷(IQCODE)),(2)3年内新发痴呆情况,以及(3)急性期后存活出院的165例患者3年内的机构化率。

结果

入院时可获得的3年机构化独立预测因素为年龄(年龄每增加1岁的调整优势比(adjOR)=1.08;95%置信区间(CI)1.03至1.15)、神经功能缺损严重程度(奥尔戈佐评分每增加1分的adjOR=0.97;95%CI 0.96至0.99)和认知障碍严重程度(IQCODE评分每增加1分的adjOR=1.03;95%CI 1至1.06)。入院时存在或随访期间出现的与3年机构化相关的因素为年龄(年龄每增加1岁的adjOR=1.17;95%CI 1.07至1.27)和任何(既往存在或新发)痴呆(adjOR=5.85;95%CI 1.59至21.59),但不是神经功能缺损的严重程度。

结论

与身体残疾的严重程度相比,年龄和认知障碍是卒中后3年机构化更重要的预测因素。

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引用本文的文献

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Poststroke dementia.中风后痴呆
Lancet Neurol. 2005 Nov;4(11):752-9. doi: 10.1016/S1474-4422(05)70221-0.
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Poststroke dementia: influence of hippocampal atrophy.中风后痴呆:海马萎缩的影响
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