大肠杆菌对TPEN的转录反应。
Transcriptional response of Escherichia coli to TPEN.
作者信息
Sigdel Tara K, Easton J Allen, Crowder Michael W
机构信息
Department of Chemistry and Biochemistry, 160 Hughes Hall, Miami University, Oxford, OH 45056, USA.
出版信息
J Bacteriol. 2006 Sep;188(18):6709-13. doi: 10.1128/JB.00680-06.
Abstract
DNA microarrays were used to probe the transcriptional response of Escherichia coli to N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine (TPEN). Fifty-five transcripts were significantly up-regulated, including all of the genes that are regulated by Zur and many that are regulated by Fur. In the same TPEN-treated cells, 46 transcripts were significantly down-regulated.
摘要
利用DNA微阵列来探究大肠杆菌对N,N,N',N'-四（2-吡啶甲基）乙二胺（TPEN）的转录反应。55个转录本显著上调，包括所有受Zur调控的基因以及许多受Fur调控的基因。在相同的经TPEN处理的细胞中，46个转录本显著下调。
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