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心脏性猝死有多突然?

How sudden is sudden cardiac death?

作者信息

Müller Dirk, Agrawal Rahul, Arntz Hans-Richard

机构信息

Medizinische Klinik II, Kardiologie und Pulmologie, Charité, Campus Benjamin Franklin, Hindenburgdamm 30, 12200 Berlin, Germany.

出版信息

Circulation. 2006 Sep 12;114(11):1146-50. doi: 10.1161/CIRCULATIONAHA.106.616318. Epub 2006 Sep 4.

DOI:10.1161/CIRCULATIONAHA.106.616318
PMID:16952983
Abstract

BACKGROUND

Out-of-hospital sudden cardiac death (SCD) is a frequent cause of death. Survival rates remain low despite increasing efforts in medical care. Better understanding of the circumstances of SCD could be helpful in developing preventive measures and facilitating proper reactions to such a pending event.

METHODS AND RESULTS

Information on cases of out-of-hospital SCD was collected in the Berlin, Germany, emergency medical system via a questionnaire. Bystander interviews were performed by the emergency physician on scene immediately after declaration of death or return of circulation. Of 5831 rescue missions, 406 involved patients with presumed cardiac arrest. Sixty-six percent had a known cardiac disease. In 72%, the arrest occurred at home, and in 67%, it occurred in the presence of an eyewitness. Information on symptoms immediately preceding the arrest was available in 80% (n = 323) of all 406 patients and in 274 of those with witnessed arrest. Symptoms were identical in the 2 groups. Typical angina was present for a median of 120 minutes in 25% of the 274 patients with witnessed arrest and in 33% with a symptom duration of less than 1 hour.

CONCLUSIONS

SCD occurs most often at home in the presence of relatives and after a longer period of typical warning symptoms. Although the much-hailed use of public access defibrillation is supported by several studies, the present results raise the question of whether educational measures and targeted educational programs tailored for patients at risk and their relatives should have a higher priority.

摘要

背景

院外心脏性猝死(SCD)是常见的死亡原因。尽管医疗救治方面的努力不断增加,但生存率仍然很低。更好地了解SCD的情况有助于制定预防措施,并促进对这种即将发生的事件做出适当反应。

方法和结果

通过问卷调查收集了德国柏林紧急医疗系统中院外SCD病例的信息。在宣布死亡或恢复循环后,急诊医生立即在现场对旁观者进行访谈。在5831次救援任务中,406次涉及疑似心脏骤停患者。66%的患者患有已知的心脏病。72%的心脏骤停发生在家中,67%的事件有目击者在场。在所有406例患者中有80%(n = 323)以及在274例有目击者的心脏骤停患者中可获得心脏骤停前即刻症状的信息。两组症状相同。在274例有目击者的心脏骤停患者中,25%的患者典型心绞痛持续时间中位数为120分钟,33%的患者症状持续时间少于1小时。

结论

SCD最常发生在家中,有亲属在场,且在出现较长时间的典型预警症状之后。尽管多项研究支持大力推广公众可及除颤,但目前的结果提出了一个问题,即针对高危患者及其亲属的教育措施和针对性教育项目是否应具有更高的优先级。

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Circulation. 2006 Sep 12;114(11):1146-50. doi: 10.1161/CIRCULATIONAHA.106.616318. Epub 2006 Sep 4.
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