Abdullah N A, Assem E S
Department of Pharmacology, University College London, UK.
Agents Actions. 1990 Apr;30(1-2):106-9. doi: 10.1007/BF01969011.
Renal vasoconstriction and ischaemia that follow in vitro antigen challenge of isolated perfused kidney of sensitized guinea-pig appears to be a self-perpetuating process, starting with a primary peak of release of vasoconstrictor mediators and followed by secondary peaks (particularly of arachidonic acid metabolites) which are probably initiated by ischaemia/reperfusion damage.
对致敏豚鼠的离体灌注肾进行体外抗原攻击后出现的肾血管收缩和缺血，似乎是一个自我延续的过程，始于血管收缩介质释放的第一个峰值，随后是第二个峰值（特别是花生四烯酸代谢产物），这可能是由缺血/再灌注损伤引发的。
