原发性干燥综合征患者外周血B淋巴细胞上CD5呈阳性。
CD5 positivity on peripheral blood B lymphocytes in patients with primary Sjögren's syndrome.
作者信息
Zeher M, Surányi P, Szegedi G
机构信息
3rd Department of Medicine, University Medical School, Debrecen, Hungary.
出版信息
Allergol Immunopathol (Madr). 1990 Mar-Apr;18(2):75-8.
PMID:1695475
Abstract
The increased number of the CD5+ (Leu 1) B cells in 9 of 17 patients with primary Sjögren's syndrome (SS) were found in this study. The percentage of CD5+ B cells that demonstrated an increased number of these cells was more than 45% in patients with pSS, and the normal level 26.3 +/- 8.8% in control subjects. The ratio of the CD5+ B cells was higher if the pSS was in the active stage.
摘要
本研究发现，17例原发性干燥综合征（SS）患者中有9例CD5+（Leu 1）B细胞数量增加。原发性干燥综合征患者中CD5+ B细胞数量增加的比例超过45%，而对照受试者的正常水平为26.3±8.8%。如果原发性干燥综合征处于活动期，CD5+ B细胞的比例会更高。
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